Stroke Trial, Recruiting NCT05195398 Sponsor: Johns Hopkins University Condition: Stroke
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Stroke Trial, Recruiting

NCT05195398
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older who have had an acute ischemic stroke (a stroke caused by a blockage), with symptoms starting within one week before being admitted to hospital
  • People whose brain MRI scan shows clear evidence of an ischemic stroke (strokes that do not show up on imaging, or mini-strokes called TIAs, are not included)
  • People who spoke English as their native language before their stroke (based on self-report)
  • People whose stroke severity score (a measure of neurological function called the NIHSS) is below 8 at a follow-up visit around 30 days after the stroke
  • People who have a low disability score (called mRS 0–2, meaning little to no disability) at that same 30-day follow-up visit

Who may not be able to join:

  • People who have had a bleeding stroke (where blood is found on a head CT or MRI scan)
  • People who have a major blockage in a large blood vessel in the brain
  • People showing certain brain function problems such as difficulty speaking or understanding language (aphasia), or difficulty being aware of one side of their body or surroundings (neglect)
  • People with a known history of dementia or a psychiatric illness that is not well managed
  • People with hearing or vision loss that has not been corrected
  • People who are unable to attend the required treatment or follow-up sessions
  • People who are unable to travel to the University of Maryland at College Park for specialised brain scanning sessions (called MEG)
  • People who have certain metal devices or implants in or near the head (such as a cardiac pacemaker, intracranial clips, metal implants in the eyes, or metal implants within 10mm of the head) that would interfere with the MEG brain scan
  • People who have claustrophobia, obesity, or any other reason that would make it difficult to remain in the MEG scanning machine for up to one hour

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Elisabeth B Marsh, MD, Johns Hopkins University

Phone: 410-550-8703

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 September 2022
Est. completion
31 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Cognition as assessed by our Cognitive Battery; Change in Functional Connectivity as assessed by MEG

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov