Alzheimer's Disease Trial, Recruiting NCT05196984 Sponsor: Massachusetts Institute of Technology Condition: Alzheimer's Disease
Back to Alzheimers Disease

Alzheimer's Disease Trial, Recruiting

NCT05196984
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 25 and 65 years old.
  • You have a confirmed diagnosis of Down Syndrome (note: mosaic Down Syndrome does not qualify).
  • You, or a legal guardian or authorized representative on your behalf, are willing to sign a consent form agreeing to take part.
  • You have been medically stable and on the same medications for at least the past 3 months.

Who may not be able to join:

  • You have been diagnosed with both Down Syndrome and Autism.
  • You have had a seizure or epilepsy in the past 24 months.
  • You have been recently diagnosed with ADHD (within the last 6 months) or have ADHD that is currently untreated.
  • You are currently taking medication to prevent or control seizures.
  • You have had a stroke within the past 24 months.
  • You have a known history of migraine headaches.
  • You are currently taking medications that are known to lower the threshold for seizures, such as certain antibiotics or some antidepressants (confirm with trial site for a full list).
  • You have significant risk of suicide or have made a suicide attempt in the past year.
  • You have behavioural challenges such as aggression, agitation, or impulsivity that may make it difficult to follow the study's requirements.
  • You are currently taking psychiatric medications, such as antidepressants or antipsychotics.
  • You have an implanted medical device, such as a pacemaker, defibrillator, deep brain stimulator, or sacral nerve stimulator.
  • You have a serious hearing or vision problem that has not been corrected.
  • You are currently pregnant.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Li-Huei Tsai, PhD, Massachusetts Institute of Technology

Phone: 6172587723

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Massachusetts Institute of Technology
Registry
ClinicalTrials.gov
Start date
6 December 2021
Est. completion
31 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Feasibility of gamma frequency stimulation; Incidence of Stimulation-Related Adverse Events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov