Phase 2 Ovarian Cancer Trial, Recruiting NCT05200260 Sponsor: Shanghai Gynecologic Oncology Group Condition: Ovarian Cancer
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Phase 2 Ovarian Cancer Trial, Recruiting

NCT05200260
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Women aged 18 years or older
  • People with a confirmed diagnosis of stage IIIC or stage IV epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal carcinoma
  • People whose scans (CT or PET/CT) show a low, medium, or high tumour spread, but with a specific spread score of 12 or below
  • People whose scans suggest that complete removal of visible tumour during surgery is likely to be achievable
  • People who agree to undergo genetic testing for BRCA (breast cancer gene) and HRD (a marker of how cancer cells repair DNA)
  • People with a reasonably good general health and activity level (confirm with trial site for exact definition)
  • People whose blood tests show that bone marrow, kidney, and liver are functioning well enough to safely receive chemotherapy and surgery (the trial site will assess specific blood test values)
  • People who are willing and able to follow the study procedures and attend follow-up appointments
  • People who have given written consent to participate in the trial

Who may not be able to join:

  • People whose ovarian cancer is not of the epithelial type, or whose tumour is classified as "borderline"
  • People with low-grade ovarian cancer
  • People with mucinous ovarian cancer
  • People whose scans suggest that complete tumour removal is not achievable — for example, due to cancer that has spread into the lung tissue, liver tissue, the lining around the lungs (in ways that cannot be surgically addressed), multiple chest lymph nodes, the brain, or bones
  • People with a known allergy or sensitivity to olaparib, bevacizumab, or any of their ingredients
  • People who have had another cancer diagnosis within the past 5 years — exceptions may apply for certain early-stage or non-active cancers such as thyroid cancer, early-stage breast cancer with no signs of return, or carcinoma in situ (confirm with trial site)
  • People with other medical conditions that would make surgery or chemotherapy unsafe or that would make it difficult to follow the study plan
  • People with other factors — such as psychological, religious, or personal circumstances — that may prevent them from giving informed consent or following through with study procedures and follow-up

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Libing Xiang, Fudan University

Phone: 86 21 64041990

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Shanghai Gynecologic Oncology Group
Registry
ClinicalTrials.gov
Start date
13 July 2022
Est. completion
1 June 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

3-year overall survival

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov