Lymphoma Trial, Recruiting NCT05255354 Sponsor: Adaptive Biotechnologies Condition: Lymphoma
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Lymphoma Trial, Recruiting

NCT05255354
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with follicular lymphoma, large B-cell lymphoma (including certain related types), or mantle cell lymphoma, confirmed through standard laboratory testing
  • You are scheduled to receive a commercially approved CAR-T cell therapy that matches FDA guidelines for your specific diagnosis, and you must be enrolled in this trial before receiving that treatment
  • The CAR-T cell product being used meets the manufacturer's required standards
  • Your disease is visible and measurable on a PET scan at the time your doctor decides to prescribe CAR-T therapy
  • A tissue sample from either your original diagnosis or a later relapse is available, so that a specific marker unique to your cancer cells (called a "clonotype") can be identified through a test called clonoSEQ

Who may not be able to join:

  • If no stored or fresh tissue sample from your diagnosis or relapse is available to identify your cancer's unique marker, you may not be eligible
  • If the laboratory test (clonoSEQ) is unable to identify your cancer's unique marker from your sample, you would be removed from the study (note: this happens in roughly 5–10% of cases — confirm with trial site)

Who will not be excluded:

  • No one will be turned away based on gender, race, ethnic background, sexual orientation, or other personal characteristics

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Heidi Simmons, PhD, Adaptive Biotechnologies

Phone: 206-279-2591

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Adaptive Biotechnologies
Registry
ClinicalTrials.gov
Start date
1 June 2022
Est. completion
1 September 2025

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Primary Outcome: Predicting Progression Free Survival

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov