COPD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged between 40 and 75 years old
- People whose condition is stable and who are taking less than 10mg of prednisone (or a similar steroid medication) per day
- People who have not smoked for at least 4 months before the screening visit and who are willing to remain smoke-free for the entire study
- People who have a current pneumococcal (pneumonia) vaccination
- People who have a current flu vaccination
- People whose lung volume reduction after a previous bronchoscopic lung volume reduction (BLVR) procedure was less than 350ml (confirm with trial site)
- People who still experience significant breathlessness (rated 2 or higher on a standard breathlessness scale) after a previous BLVR procedure
- People who still have endobronchial valves in place from a previous BLVR procedure
- People who are willing and able to attend all required follow-up visits and complete all study procedures
Who may not be able to join:
- People who produce more than about 4 tablespoons of mucus per day
- People who have had a heart attack within the 6 months before screening
- People with heart failure that is not currently controlled
- People who have had three or more episodes of pneumonia in the past year
- People who have had three or more COPD flare-ups in the past year
- People who have previously had a lung transplant, lung volume reduction surgery, or surgical removal of part or all of a lung
- People with a significant airway condition called bronchiectasis
- People who are unable to safely stop taking blood thinners or anti-clotting medications for 7 days
- People with uncontrolled high blood pressure in the lungs, or a related heart condition, as shown on a heart ultrasound done within the last 3 months
- People whose heart pumping function is below 40%, as shown on a heart ultrasound done within the last 3 months
- People with a resting heart rate below 50 beats per minute, certain irregular heart rhythms, or a sustained rapid heart rhythm
- People with carbon dioxide levels above a certain threshold in their blood when breathing normal air at screening (confirm with trial site)
- People with oxygen levels below a certain threshold in their blood when breathing normal air at screening (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Prove that inter-lobar fissures can be completed to at least 95% in severe emphysema patients with previously failed bronchoscopic lung volume reduction; Incidence of severe adverse events
Can't join this trial?
Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.