Phase 2 Asthma Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have completed the consent process and signed the required paperwork
- Men and women between 18 and 70 years old (inclusive)
- People who developed ongoing breathing symptoms — such as cough, shortness of breath, wheezing, and/or chest tightness — during or after military deployment to Southwest Asia after 9/11/2001, and whose breathing test results meet specific criteria for deployment-related asthma (confirm with trial site for full details on accepted test results)
- People who are able to perform breathing tests reliably according to standard guidelines
- People of any racial or ethnic background
- People with a smoking history of 15 pack-years or less, and who have not smoked in the last 3 months
- People whose asthma is not well controlled at the start of the trial, based on standard asthma questionnaire scores (confirm with trial site)
Who may not be able to join:
- People who have had a respiratory tract infection in the 4 weeks before the first visit
- People who have had an emergency department visit for a lung-related reason in the 4 weeks before the first visit
- People who have taken a course of oral or systemic steroid medication for any reason in the 4 weeks before the first visit (single-dose injections into a joint require a 2-week gap before the first visit)
- People with significant other medical conditions — such as heart disease, cancer, uncontrolled diabetes, or other chronic lung diseases — as determined by the lead investigator
- People with chronic kidney failure above a certain level, identified by a blood test at the first visit
- People who are pregnant, or who test positive for pregnancy at any point during the study
- People with a known intolerance or allergy to L-arginine or L-citrulline (the study supplements)
- People currently taking a class of medications called PDE5 inhibitors or oral mononitrates (confirm with trial site if unsure whether a current medication falls into these categories)
- People who, in the investigator's opinion, are unlikely to be able to complete all study requirements
- People for whom, in the investigator's opinion, taking part would carry too much personal health risk
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Fernando Holguin, MD, MPH, University of Colorado Denver- Anschutz Medical Campus
Phone: 1-844-365-0852
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in Asthma Control Questionnaire; Change in FeNO values
Can't join this trial?
Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.