Ovarian Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Women who have not yet reached menopause and have a confirmed harmful gene mutation in one or more of the following genes: BRCA1, BRCA2, BRIP1, RAD51C, PALB2, or RAD51D.
• Women aged 25–40 if they carry a BRCA1 mutation, aged 25–45 if they carry a BRCA2 mutation, or aged 30–50 if they carry a BRIP1, RAD51C, RAD51D, or PALB2 mutation (if multiple mutations are present, the age range is based on the BRCA mutation).
• Women who no longer need their fallopian tubes for natural pregnancy, though future plans to use IVF are acceptable.
• Women who still have at least one fallopian tube remaining.
• Women who have had a previous cancer diagnosis, as long as it was not ovarian, fallopian tube, or peritoneal cancer.
• Women who have given their informed written consent to participate.

Who may not be able to join:

• Women who have gone through menopause, either naturally or as a result of cancer treatment (defined as having had no periods for 12 months without another medical explanation).
• Women who already plan to have a full removal of their ovaries and fallopian tubes within two years of joining the trial, if that plan is clear at the time of enrollment.
• Women who are not legally able to consent for themselves.
• Women who have already had both fallopian tubes surgically removed.
• Women who have a personal history of ovarian, fallopian tube, or peritoneal cancer.
• Women who currently have signs of, a diagnosis of, or are receiving treatment for an active cancer (note: certain hormone-related medications such as Tamoxifen, Aromatase Inhibitors, and SERMs are permitted — confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.