Phase 2 Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are between 55 and 90 years old
- You are able to understand and agree to participate in the study on your own
- If you are a healthy volunteer: you have no history of Alzheimer's disease or related memory/thinking disorders
- If you have Alzheimer's disease: you have been medically diagnosed with Alzheimer's disease (either the typical memory-loss type or an unusual form), your condition ranges from mild thinking/memory concerns to moderate dementia, and you scored at or above a certain level on standard memory and thinking tests (confirm with trial site)
- If you are a BAnD subject: you were referred through the Brain Aging and Dementia (BAnD) research registry
Who may not be able to join:
- You have metal devices or implants in your body that are not safe for MRI scans, such as a pacemaker, aneurysm clips, artificial heart valves with metal parts, metal fragments, or similar items
- You have tattoos near your eyes or wear items with metal that cannot be removed (confirm with trial site)
- You have a medical condition that raises your risk of seizures, severe anxiety in enclosed spaces (claustrophobia), or a higher-than-normal risk of cardiac arrest
- Your kidneys do not filter blood well enough (based on a blood test result), which would prevent you from receiving the contrast dye used during certain scans
- You have already been exposed to a significant amount of medical radiation in the past 12 months, above the limits set by Massachusetts General Hospital
- You are currently pregnant or breastfeeding; if there is any chance you could be pregnant and you have not gone through menopause, a urine pregnancy test will be required before you can join
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Ciprian Catana, MD, PhD, Massachusetts General Hospital
Phone: 617-643-4885
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Concentration of fibrin in the brains of ADRD subjects and healthy controls
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.