Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 years or older
- People who have had a stroke caused by a blockage (not bleeding) on one side of the brain that is causing symptoms; a second silent (symptom-free) stroke on the other side is still permitted
- People who have weakness in the shoulder and/or fingers of the arm affected by the stroke, measured within 48 to 96 hours of the stroke occurring
- People who are able and willing to sign a consent form within 24 to 96 hours of the stroke occurring
- People who are willing and able to attend all study visits, including an in-person visit at 90 days
- People who speak English or Spanish fluently
Who may not be able to join:
- People who had a pre-existing injury or condition affecting the stroke-weakened arm before the stroke occurred
- People who are legally blind
- People who have a complete loss of sensation on the stroke-affected side of the body
- People who are unable to lift their shoulder or straighten their fingers on the unaffected (stronger) arm when asked verbally
- People whose stroke affected only the cerebellum (the balance-and-coordination area at the back of the brain)
- People who had a symptomatic stroke anywhere in the brain within 30 days before the current stroke
- People already enrolled in another trial targeting the current stroke (either for acute treatment or for recovery) after this study's baseline assessments have begun
- People who are not expected to be able to complete follow-up visits through 90 days
- People whose thinking or communication difficulties would prevent them from giving informed consent themselves
- People with a major medical, neurological, or psychiatric condition that substantially affects their ability to function
- People with a serious non-stroke medical condition where survival to 90 days is unlikely
- People who are pregnant
- People who cannot have an MRI without contrast dye — for example, due to certain metal implants, metal fragments in the body, or severe claustrophobia
- People who cannot receive transcranial magnetic stimulation (TMS), including those with:
- An implanted heart device such as a pacemaker or defibrillator
- Any electronic device in the body at or above the neck (such as a cochlear implant, deep brain stimulator, or certain other implanted devices)
- A metal implant inside the skull
- A skull defect related to the current stroke
- A seizure that occurred after the current stroke began
- A seizure within the last 12 months while taking anti-seizure medication
- A previous serious reaction to TMS
- People for whom the required study assessments and procedures cannot be completed within the required time windows after stroke onset (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Pooja Khatri, MD, Yale University
Phone: 203-747-4730
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Upper Extremity-Fugl Meyer (UE-FM) for AIM 1; Action Research Arm Test (ARAT) for AIM 2
Can't join this trial?
Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.