Phase 1 Lymphoma Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have given written consent to take part (or whose legal representative has done so on their behalf)
• People who are willing and able to follow all the steps required by the study
• People aged 18 or older
• People whose general physical functioning is rated at a level of 2 or below on a standard cancer performance scale (this measures how much a condition affects daily activity — confirm with trial site)
• People with a solid tumour cancer that has spread to other parts of the body, where a type of targeted radiation treatment called SBRT has been assessed as suitable by a radiation oncologist
• People with lymphoma, if the principal investigator determines this is appropriate
• People whose cancer treatment plan has not changed in the two months before starting SBRT
• People who are able to attend daily PET scans after SBRT
• People whose recent blood and safety test results meet the hospital's standard requirements for people receiving cancer treatment, or are accepted at the investigator's discretion
• Women who could become pregnant must have a negative pregnancy test (urine or blood) before joining
• People of childbearing potential (defined as not having been surgically sterilised, or, for women, not having been without a menstrual period for more than one year) must agree to use two forms of contraception or avoid heterosexual activity during the study and for at least 30 days after the last dose of the study imaging agent

Who may not be able to join:

• People with spleen disorders or who have had their spleen removed, if the principal investigator considers this would affect the study imaging results
• People with any uncontrolled illness, including an ongoing or active infection
• People who have previously had an allergic reaction to substances with a similar chemical or biological makeup to the study imaging agent (CD8 PET tracer)
• People with serious non-cancer-related conditions that the investigator believes could affect the study's objectives
• Women who are pregnant or breastfeeding (the study imaging agent carries a potential risk of harm to an unborn baby or to a nursing infant)
• People with any other condition that the investigator considers would make participation unsafe
• People who, in the investigator's opinion, may not be able to follow all study procedures, including any practical or logistical reasons

Important: Always verify eligibility with the trial site directly before applying.