Prostate Cancer Trial, Recruiting NCT05396872 Sponsor: University of California, San Francisco Condition: Prostate Cancer
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Prostate Cancer Trial, Recruiting

NCT05396872
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Patients (Stage 1):

  • Adults aged 18 or older
  • Able to understand and follow the study procedures for the full duration of the study
  • Able to understand and willing to sign a written consent form
  • Able to speak, read, and understand English
  • Has a confirmed diagnosis of locally advanced, metastatic, or castration-resistant prostate cancer, documented in medical records
  • Has an upcoming appointment with a blood cancer or oncology specialist where genetic testing or targeted treatment is expected to be discussed

Patients (Stage 2):

  • Took part in Stage 1 of the study
  • Has already completed genetic testing (either from blood/saliva or from the tumour) for prostate cancer
  • Able to understand and follow the study procedures for the full duration of the study

Patients (Stage 3):

  • Adults aged 18 or older
  • Able to understand and follow the study procedures for the full duration of the study
  • Able to understand and willing to sign a written consent form
  • Able to speak, read, and understand English
  • Has a confirmed diagnosis of high-risk, very high-risk, locally advanced, metastatic, or castration-resistant prostate cancer, documented in medical records
  • Has an upcoming appointment with a blood cancer or oncology specialist where germline (hereditary) genetic testing is expected to be discussed

Caregivers (Stage 1 & Stage 3):

  • Adults aged 18 or older
  • Named by a patient participant as someone involved in that patient's care, and willing to take part in interviews
  • Able to give verbal consent
  • Able to speak and understand English

Caregivers (Stage 2):

  • Took part in Stage 1 of the study
  • Is a partner, family member, or friend identified by a Stage 2 patient participant as their caregiver

Healthcare providers (Stage 1):

  • A specialist doctor or nurse practitioner in blood cancers/oncology or genetics (clinical fellows past their first year are also eligible)
  • Has discussed hereditary genetic testing, tumour genetic testing, or targeted therapy with a qualifying prostate cancer patient at the San Francisco VA Health Care System (SFVAHCS) within the past 90 days
  • Able to provide consent by email

Healthcare providers (Stage 2 – SFVAHCS):

  • Took part in Stage 1
  • Is a medical oncology doctor who has discussed genetic testing or targeted therapy with an advanced prostate cancer patient within the past 30 days, OR a genetics doctor who has done so within the past 90 days

Healthcare providers (Stage 2 – Non-SFVAHCS):

  • Is a lead investigator at a Precision Oncology Program for Cancer of the Prostate (POPCaP) site, OR a medical oncology doctor who has discussed genetic testing or targeted therapy with an advanced prostate cancer patient within the past 30 days, OR a genetics doctor who has done so within the past 90 days (confirm with trial site)
  • Note: Clinical fellows are not eligible for the non-SFVAHCS provider group
  • Able to understand and follow the study procedures for the full duration of the study

Healthcare providers (Stage 3):

  • A doctor (MD) at SFVAHCS trained in medical oncology, or currently completing a clinical fellowship in that area
  • Has discussed hereditary genetic testing for prostate cancer with an SFVAHCS patient within the past year, or plans to do so
  • Able to provide verbal consent

Who may not be able to join:

Patients (Stage 1):

  • People who are undergoing genetic testing and have already received their genetic test results before joining the study

Patients (Stage 3):

  • People who have previously had hereditary (germline) genetic testing
  • People who already took part in Stage 1 of the study specifically for germline testing

Caregivers and providers (all stages):

  • People who do not meet the inclusion criteria listed above for their relevant group and stage

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Daniel Kwon, MD, University of California, San Francisco

Phone: 877-827-3222

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
12 May 2022
Est. completion
31 July 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Mean score on the Decisional Conflict Scale (DCS) (Stage 1); Proportion of participants with a total score of >37.5 on the DCS (Stage 1); Proportion of participants enrolled (Stage 3); Proportion of participants providing reason for not enrolling (Stage 3)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov