Phase 1 Prostate Cancer Trial, Recruiting NCT05398302 Sponsor: Jonsson Comprehensive Cancer Center Condition: Prostate Cancer
Back to Prostate Cancer

Phase 1 Prostate Cancer Trial, Recruiting

NCT05398302
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have prostate cancer that has been confirmed through laboratory testing of tissue samples
  • People whose cancer has been determined eligible for a specific treatment called 177Lu-PSMA-617, either through a special access program or as part of an approved trial
  • People whose scans (PET/CT imaging) show that cancer has spread to lymph nodes or soft tissue in a way that allows a guided tissue sample to be taken
  • People whose blood platelet count is above 75,000/ul, tested within 14 days before the tissue sample procedure
  • People whose blood clotting levels (measured by specific tests called PT/INR and PTT) are within an acceptable range, tested within 14 days before the tissue sample procedure
  • People who take blood-thinning medications (such as warfarin or aspirin) may still be considered, provided the treating doctor determines it is safe to pause those medications for one week before the procedure (confirm with trial site)

Who may not be able to join:

  • People who have significant bleeding disorders, whether present from birth or developed over time (for example, von Willebrand's disease or conditions affecting blood clotting factors)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Johannes Czernin, UCLA / Jonsson Comprehensive Cancer Center

Phone: 310-794-3421

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Jonsson Comprehensive Cancer Center
Registry
ClinicalTrials.gov
Start date
26 April 2024
Est. completion
31 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Proportion of patients with a successful evaluable biopsy with molecular and cellular alterations after radioligand therapy (RLT)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov