Psoriasis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People of any sex who are admitted to the Dermatology department at the CHU of Nice hospital with moderate to severe psoriasis (measured by a skin severity score of 10 or above)
• People with a clinical diagnosis of plaque psoriasis confirmed by a dermatologist, with or without type 2 diabetes (defined by a blood sugar marker called glycated haemoglobin above 7%)
• People covered by a social security scheme
• People who have given their free and informed consent to participate
• For the control group: people without psoriasis or other inflammatory skin conditions, with or without type 2 diabetes, who have given their free and informed consent

Who may not be able to join:

• People who are under 18, unable to consent, or unwilling to give free and informed consent
• Women who are pregnant or breastfeeding
• People currently excluded from participating in other biomedical research studies
• People who have a generalised chronic inflammatory disease or another inflammatory skin condition
• People who have taken certain medications recently, including: oral corticosteroids or immune-modifying drugs in the past month, corticosteroid creams or treatments in the past 15 days, certain targeted biological therapies (anti-IL-23 or anti-IL-12/23) for less than 3 months, or other biological therapies (anti-IL-17 or anti-TNF) for less than 1 month
• People for whom a small skin biopsy (tissue sample) would be medically unsafe — for example, those with a known bleeding disorder, who take blood-thinning medications, who have an allergy to a local anaesthetic called xylocaine, who have a history of raised/keloid scarring, or who have a congenital immune deficiency

Important: Always verify eligibility with the trial site directly before applying.