Psoriasis

**Who might be able to join this trial:** - You have been diagnosed with plaque psoriasis (with or without psoriatic arthritis) for at least 6 months before the start of the study - At least 10% of your body surface area is affected by psoriasis at both the screening and start of the study - Your psoriasis scores at l...

"Who might be able to join this trial: - You are 18 years old or older and have been diagnosed with the most common form of psoriasis (called plaque psoriasis) for at least 12 months before starting the study - Your psoriasis has been rated as moderate or severe by a doctor, based on standard scoring measurements - You...

**Who might be able to join this trial:** - You must be currently taking Methotrexate (MTX) at a steady dose — you need to have been on it for at least 3 months, at a dose between 15mg and 25mg per week, with no dose change in the 4 weeks before joining (a lower dose of 10mg/week may be allowed in certain circumstance...

Who might be able to join this trial: - You have had moderate to severe plaque psoriasis for at least 6 months before joining the study, with significant affected areas on the palms of your hands and/or soles of your feet, plus at least one psoriasis plaque elsewhere on the body. - Your psoriasis has not been well cont...

**Who might be able to join this trial:** - You are a man or woman aged 18 to 75 years old - You have had moderate to severe plaque psoriasis that has been stable for at least 6 months before the start of the trial - Your psoriasis covers at least 10% of your body surface area and meets certain severity scores measured...

**Who might be able to join this trial:** - You have been diagnosed with plaque-type psoriasis (with or without psoriatic arthritis) for at least 6 months before starting the study. - Your psoriasis has been rated as moderately to severely active based on a standard medical scoring system called PASI (score of 12 or h...

**Who might be able to join this trial:** - You have been diagnosed with plaque-type psoriasis (with or without psoriatic arthritis) for at least 6 months before the start of the study - Your psoriasis is rated as moderately severe or worse based on a standard medical scoring system called PASI (confirm with trial site...

**Who might be able to join this trial:** - You have been diagnosed with Psoriatic Arthritis (a condition causing joint pain and skin symptoms) using a specific set of recognised diagnostic guidelines. - Certain blood tests (Rheumatoid factor and anti-CCP antibodies) have come back negative. - You have active plaque ps...

Who might be able to join this trial: - You have been diagnosed with chronic plaque psoriasis for at least 6 months before the study starts. - You have moderate-to-severe psoriasis in the genital area at the time of screening and at the start of the study. - You also have plaque psoriasis somewhere on your body outside...

**Who might be able to join this trial:** - You are between 18 and 70 years old (male or female) - You have been diagnosed with plaque psoriasis for at least 6 months - If you are a woman who could become pregnant, you must have a negative pregnancy test and must not currently be pregnant, breastfeeding, or planning to...

Who might be able to join this trial: - You are between 18 and 70 years old - You have had chronic plaque psoriasis for at least 6 months before the screening visit - Your psoriasis is rated as moderately severe or worse based on standard medical scoring tools that measure the area and severity of your skin condition (...

**Who might be able to join this trial:** - You have a history of moderate to severe chronic plaque psoriasis and have already completed one of the specific earlier studies linked to this trial. - Your doctor believes you are a suitable candidate to continue receiving the study drug (risankizumab) on an ongoing basis....

**Who might be able to join this trial:** - You must be at least 18 years old - You have had chronic plaque psoriasis for at least 6 months before the screening visit - Your psoriasis is considered moderate to severe, based on specific medical measurements of how much of your body is affected and how severe it looks (c...

Who might be able to join this trial: - You have had moderate to severe plaque psoriasis (raised, scaly skin patches) for at least 6 months, confirmed by a doctor's examination. - Your nail psoriasis is moderate to severe, based on specific scoring measurements taken at your screening and first visits. - Your skin psor...

**Who might be able to join this trial:** - You are between 18 and 75 years old at the time of screening - You have been diagnosed with Palmoplantar Pustulosis (PPP), meaning you have had visible, non-infected blisters/pustules on your palms and/or soles for more than 3 months, with or without psoriasis on other parts...

**Who might be able to join this trial:** - You have been diagnosed with moderate to severe plaque psoriasis for at least 6 months before the study starts. - You have been taking secukinumab or ixekizumab (specific biologic medications) as directed for at least 6 months, but the treatment is not working as well as expe...

**Who might be able to join this trial:** - You are able to read, write, and sign a consent form; if you are a teenager, a parent or guardian can provide consent on your behalf - You are male or female and aged 12 years or older - You have scalp psoriasis that has been rated at least "mild" by the investigating doctor...

Who might be able to join this trial: **For Atopic Dermatitis (eczema):** - You have been diagnosed with atopic dermatitis (eczema) for at least 3 months - Your eczema has been rated as mild or moderate by a doctor using a standard assessment scale - Your eczema covers between 5% and 20% of your body surface area **F...

**Who might be able to join this trial:** - Young people aged 12 to under 18 years old (Group 1), or children aged 4 to under 12 years old (Group 2), of any gender - Have been diagnosed with plaque psoriasis for at least 6 months - Have a moderate to severe level of psoriasis - Have been considered a suitable candidat...

**Who might be able to join this trial:** - Adults aged 18 or older - People who are willing and able to sign a consent form before any study activities begin, and who are able to follow all study procedures - People who have been diagnosed with plaque psoriasis for at least 6 months, whose condition is currently suita...

**Who might be able to join this trial:** - You have moderate-to-severe plaque psoriasis and your doctor considers you a candidate for light therapy or systemic (whole-body) medication to treat it, including a medicine called ustekinumab. - You are a current cigarette smoker. - You have been diagnosed with high blood...

**Who might be able to join this trial:** - You have had moderate to severe plaque psoriasis that has been stable for at least 6 months. - At the screening and start of the trial, your psoriasis affects at least 10% of your body surface area and scores highly enough on two standard psoriasis severity measurement scales...

Who might be able to join this trial: - You have been diagnosed with plaque psoriasis or psoriatic arthritis by a skin specialist (dermatologist) - You are 18 years of age or older - You are starting a specific biologic or systemic medication for the first time (meaning you have not taken this type of drug before) - Yo...

Who might be able to join this trial: - People who have been clinically diagnosed with psoriasis. - People who are 19 years of age or older. - People with any skin tone type (the trial includes all six Fitzpatrick skin types, which covers the full range of skin tones from very fair to very dark). Who may not be able t...

Who might be able to join this trial: - You have been diagnosed by a doctor with atopic dermatitis (eczema), psoriasis, or an autoimmune skin disease - You are willing and able to give written consent to take part in the trial Who may not be able to join: - You do not wish to take part in the trial - If you are under...

"Who might be able to join this trial: - Adults aged 18 or older, either male or female - People who have been diagnosed with chronic plaque-type psoriasis for at least 6 months - People whose psoriasis is rated as moderate to severe, based on specific skin measurement scores (BSA ≥10, PASI ≥12, and IGA ≥3 — the trial...

Who might be able to join this trial: - Adults aged 18 or older, of any gender - People who have been diagnosed with chronic plaque-type psoriasis - People whose psoriasis covers between 2% and 10% of their body surface area - People whose doctor has rated their psoriasis as a score of 2 or higher on a standard severit...

**Who might be able to join this trial:** - Children and young people who are between 6 years old and 16 years and 11 months old at the time of joining the study. - People whose parent or legal guardian (and the participant themselves, where appropriate) have given written and verbal agreement to take part. - People w...

**Who might be able to join this trial:** - People aged 18 years or older - People with mild to severe plaque psoriasis, where at least 2% of the body's skin surface is affected, and where a doctor has confirmed the severity using standard psoriasis scoring tools **Who may not be able to join:** - People currently tak...

Who might be able to join this trial: - People who have been diagnosed with chronic plaque-type psoriasis, either based on a doctor's clinical assessment or confirmed through a tissue sample (biopsy) - People who are willing to sign a consent form showing they understand what the study involves and agree to take part...

"Who might be able to join this trial: - You must be an adult aged 18 or older (male or female) - You must have been diagnosed with chronic plaque psoriasis (a common form of psoriasis that causes raised, scaly patches on the skin) - Your psoriasis must be affecting between 2% and 10% of your body surface area - You mu...

**Who might be able to join this trial:** - Adults aged 18 or older, of any gender - People diagnosed with moderate-to-severe chronic plaque-type psoriasis, confirmed by specific clinical scores measuring how much of the body is affected and how severe the condition is (confirm with trial site for exact score threshold...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have been diagnosed with chronic plaque-type psoriasis - People whose psoriasis affects between 3% and 8% of their body surface area - People who have been receiving treatment with Taltz (ixekizumab) for at least 24 weeks - Women who could...

Who might be able to join this trial: - You have been diagnosed with psoriasis by a skin specialist (dermatologist) at a clinic. Who may not be able to join: - There are no listed reasons that would prevent someone from joining this trial. Important: Always verify eligibility with the trial site directly before apply...

**Who might be able to join this trial:** - You are over 21 years old. - A dermatologist (skin doctor) has diagnosed you with plaque-type psoriasis specifically. - Your psoriasis is considered moderate to severe, based on specific scores measured by a doctor (covering how widespread and serious your skin condition is,...

Who might be able to join this trial: - You are 18 years old or older and have been diagnosed with psoriasis Who may not be able to join: - You are unable to cooperate with or take part in the requirements of the study - You are unable to understand and sign the consent form agreeing to take part in the trial Importa...

**Who might be able to join this trial:** - You are 18 years old or older - You can be male or female - You have been diagnosed with psoriasis by a skin doctor (dermatologist) for at least 2 years (this applies to at least 30% of participants in the trial) - You are willing and able to give your consent to take part -...

**Who might be able to join this trial:** - You have been diagnosed with a chronic inflammatory joint condition, such as rheumatoid arthritis, spondyloarthritis, or psoriatic arthritis, OR you have been diagnosed with osteoporosis (either as a primary condition or caused by another health issue) - You are covered by Na...

**Who might be able to join this trial:** - You are an adult (over 18 years old) - You have been diagnosed with skin psoriasis - You have agreed to take part and signed a consent form - You are covered by health insurance (note: AME coverage has specific rules — confirm with trial site) - *(For Group 1 only)* You need...

**Who might be able to join this trial:** - You have been diagnosed with plaque-type psoriasis by a board-certified skin doctor, a dermatology nurse practitioner, or through a skin biopsy test. - Your health insurance covers the biologic medication ustekinumab (Stelara) AND at least one of the following biologic medica...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with moderate to severe psoriasis, or psoriasis that affects more than 5% of your body surface area **Who may not be able to join:** - You have taken medicines that suppress the immune system (such as certain tablets...

**Who might be able to join this trial:** - People of any sex who are admitted to the Dermatology department at the CHU of Nice hospital with moderate to severe psoriasis (measured by a skin severity score of 10 or above) - People with a clinical diagnosis of plaque psoriasis confirmed by a dermatologist, with or witho...

**Who might be able to join this trial:** - You are 18 years old or older - You have health insurance coverage - You experience significant itching, rated 4 or higher on a scale of 0 to 10 - You have been diagnosed with plaque psoriasis **without** joint involvement, with moderate-to-severe skin coverage (confirmed by...

Who might be able to join this trial: - People who are between 18 and 75 years of age - People who have moderate to severe chronic psoriasis covering at least 3% of their body surface area - People whose psoriasis has been present for at least 6 months - People whose condition has been assessed as needing systemic (who...

**Who might be able to join this trial:** - Adults aged 18 or older of any sex who have at least one psoriasis skin plaque larger than 5 cm² (roughly the size of a large postage stamp), with a psoriasis diagnosis made at least one year before joining, where the condition ranges from mild (faint thickening, light pink...

**Who might be able to join this trial:** - People who have been diagnosed with psoriatic arthritis using a specific set of recognised medical criteria (called CASPAR criteria) - People whose psoriatic arthritis is currently active, meaning at least one joint is visibly swollen - People whose psoriatic arthritis disea...

**Who might be able to join this trial:** - People who have been diagnosed with Crohn's disease (CD) or plaque psoriasis (PsO) - People whose condition has not responded well to standard treatments - People with currently active disease — for Crohn's disease, this means moderate or higher disease activity based on reco...

Who might be able to join this trial: - You have been diagnosed with plaque psoriasis by a skin doctor (dermatologist) - You are starting one of two specific medications for the first time: deucravacitinib or apremilast - You are already signed up to a patient registry called the CorEvitas Psoriasis Registry and have a...

Who might be able to join this trial: - People with a scalp psoriasis severity score (called a PSSI score) of 12 or higher, indicating moderate to severe scalp psoriasis Who may not be able to join: - People who have taken medications that suppress the immune system in the last 4 weeks - People who are currently pregn...

Who might be able to join this trial: - People who are 18 years of age or older - People who have moderate-to-severe psoriasis, based on specific skin assessment scores measured by a doctor (covering a large enough area of the body and rated at a certain level of severity) Who may not be able to join: - People who hav...

Who might be able to join this trial: - You are between 18 and 70 years old - You can read and write in English - You are willing to give your consent and understand what the study involves, including any possible risks - You have been diagnosed with rheumatoid arthritis, psoriatic arthritis, psoriasis, or ankylosing s...

Who might be able to join this trial: - You have been diagnosed by a dermatologist (skin doctor) with an inflammatory skin disease. - You are willing and able to give your written consent to take part in the study. Who may not be able to join: - You (or your legal guardian, if applicable) are unable to provide written...

**Who might be able to join this trial:** *All participants:* - People who are willing to take part and are able to give their informed agreement before any study procedures begin. - People who are willing to follow all study procedures and are available for the full duration of the study. *Healthy volunteers:* - Peo...

**Who might be able to join this trial:** - You have been diagnosed with psoriasis that significantly affects the genital area (with a severity score of 3 or higher on a standard medical scale). - Your doctor has decided you need a biologic treatment (a type of medication given by injection), and the specific medicatio...

**Who might be able to join this trial:** - People who are 18 years of age or older - People with moderate-to-severe plaque psoriasis who are currently being treated with a biologic therapy (a type of medication that targets specific parts of the immune system, such as TNFα antagonists, IL-12/23 antagonists, or IL-17 a...

**Who might be able to join this trial:** - You are between 18 and 65 years old (male or female) - You have been diagnosed with plaque psoriasis according to standard medical criteria - Your psoriasis has been identified as matching a Traditional Chinese Medicine pattern called "Blood-heat syndrome" (confirm with trial...

Who might be able to join this trial: - People who have been diagnosed with a skin condition called GPP (Generalized Pustular Psoriasis) by a dermatologist or qualified skin specialist. - People who are at least 18 years old and meet the legal age of consent required in the country where the research is taking place. -...

**Who might be able to join this trial:** - You are about to start treatment with a type of medication called an anti-IL-17 antibody (a specific kind of drug that targets the immune system) **Who may not be able to join:** - You are currently pregnant - Your lung function is below a certain level, specifically if your...

**Who might be able to join this trial:** - People who are currently experiencing a moderate-to-severe flare of Generalized Pustular Psoriasis (GPP), meaning their condition scores 3 or higher on a standard doctor-rated scale, new or worsening pustules are present with a pustule-specific score of 2 or higher, and at l...

Who might be able to join this trial: - You are 19 years of age or older - You have been diagnosed with moderate-to-severe plaque psoriasis - Your doctor has determined that you are a suitable candidate for light therapy or systemic (whole-body) medication - You are about to start taking deucravacitinib as directed by...

**Who might be able to join this trial:** - People who are able to fully understand what the trial involves, including possible side effects, are willing to complete the study, and are able to sign a consent form. - Adults between 18 and 70 years old (inclusive). - Male participants who weigh at least 50 kg, and femal...

Who might be able to join this trial: - You are Japanese and are 18 years of age or older - A doctor has diagnosed you with plaque psoriasis - You are about to start treatment with either deucravacitinib or apremilast (as directed by your doctor and the medication's approved guidelines) for the first time - You have re...

**Who might be able to join this trial:** - You have skin damage that is known or suspected to be caused by your immune system attacking your own body (autoimmune, immune-related, or inflammatory condition) - You have a blistering skin disease caused by the immune system, such as pemphigus or pemphigoid - You have a sy...

**Who might be able to join this trial:** - You are 18 years old or older - You have been formally diagnosed with plaque psoriasis by a qualified skin specialist (dermatologist) - You are currently being treated with one of these three medications — secukinumab, ixekizumab, or guselkumab — and have been taking it at th...

**Who might be able to join this trial:** - You have been diagnosed with chronic plaque psoriasis for at least 12 months before the screening visit. - Your psoriasis is considered moderate to severe, based on at least one of the following measures used by your doctor (confirm with trial site). - You have been prescrib...

**Who might be able to join this trial:** - The child or teen must be between 6 and 17 years old (inclusive) at the time of signing the consent forms - They must have been diagnosed with moderate to severe plaque psoriasis for at least 3 months before the screening visit - At both the screening and baseline appointmen...

Who might be able to join this trial: - People who took part in a previous related study (HB0034-04) and completed at least the Week 12 visit of that study - People whose doctor considers them a suitable candidate for ongoing long-term treatment for their condition - Men and women of reproductive age who do not plan to...

Who might be able to join this trial: - You have been diagnosed with one of these conditions: Rheumatoid Arthritis, Psoriatic Arthritis, Spondyloarthritis, Ankylosing Spondylitis, Systemic Sclerosis, Systemic Lupus Erythematosus, or Sjogren's Disease - You have recently been prescribed a new medication to suppress your...

**Who might be able to join this trial:** - Adults over 18 years old, of any sex - People who have a history of psoriasis affecting at least 3% of their body surface area, and who are willing to allow the lead researcher to perform skin biopsies on an affected area (this part is optional) - People who also have a diagn...

**Who might be able to join this trial:** - You are between 18 and 75 years old (inclusive) - You have been diagnosed with chronic plaque psoriasis for at least 6 months before joining the trial - Your psoriasis is considered moderate to severe, based on specific scores measuring how much of your skin is affected and h...

Who might be able to join this trial: **For people with Psoriatic Arthritis:** - People diagnosed with peripheral or axial Psoriatic Arthritis using recognised medical classification systems, who also have signs of active disease confirmed by clinical assessment and ultrasound imaging (such as joint inflammation, tend...

**Who might be able to join this trial:** - People who are willing to sign a consent form before any study-related procedures begin - People who have been diagnosed with psoriatic arthritis according to the 2006 CASPAR classification standard at the time of screening - People whose psoriatic arthritis is currently act...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of signing the consent form, of any gender - People who have been diagnosed with moderate to severe plaque psoriasis - People whose doctor has assessed them as suitable to receive vunakizumab as their treatment - People who...

Who might be able to join this trial: - You are 18 years old or older - A doctor has diagnosed you with moderate to severe plaque psoriasis - You are about to start treatment with a medication called deucravacitinib for the first time - You are willing to take part in the study Who may not be able to join: - You are c...

**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with psoriasis - People who are currently receiving care for psoriasis at a specialist (secondary care) clinic - People who are able to walk for 30 minutes at a slow pace (around 2km), or wheelchair users who have...

**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with psoriasis - People whose psoriasis treatment has been stable for the last 6 months - People whose psoriasis has a significant impact on quality of life, as measured by a standard scoring tool called the DLQI (a score above...

**Who might be able to join this trial:** - Men and women aged 18 or older but under 45 years old - People who have plaque psoriasis but do not have psoriatic arthritis (a joint condition related to psoriasis) - People whose psoriasis is mild, with a disease severity score (called PASI) between 2 and 6 - People who ha...

**Who might be able to join this trial:** - You have moderate to severe psoriasis, with a disease severity score (called PASI) above 10 - You have been receiving a specific type of biologic medication (called an anti-IL-23 therapy) for at least 6 months (this applies to the treatment group) - While on this medication,...

**Who might be able to join this trial:** - People who have agreed to take part voluntarily and have signed a consent form - People aged 18 to 75 years old at the time of signing the consent form - People who have had plaque psoriasis for at least 6 months before the start of the study - People whose psoriasis require...

**Who might be able to join this trial:** **For the single-dose part of the study (SAD):** - You are a healthy adult between 18 and 45 years old - Men must weigh at least 50 kg and women at least 45 kg, and everyone must weigh no more than 110 kg, with a body mass index (BMI) between 18 and 28 - Your general health ch...

**Who might be able to join this trial:** - People who have been diagnosed with moderate-to-severe plaque psoriasis by a dermatologist or other qualified clinician experienced in treating psoriasis - People with a body mass index (BMI) of 30 or above (classified as obese), or a BMI between 27 and under 30 (classified...

**Who might be able to join this trial:** - You have been diagnosed with chronic plaque psoriasis (a long-term skin condition causing red, scaly patches) - You are in obesity class I (this generally means a BMI between 30 and 34.9 — confirm with trial site) - You have been told you are prediabetic (your blood sugar lev...

Who might be able to join this trial: - You are between 18 and 70 years old (inclusive) at the time of signing the consent form - You have been diagnosed with plaque psoriasis for at least 6 months before your screening visit - At least 10% of your body surface area is affected by psoriasis at the time of screening and...

**Who might be able to join this trial:** - You have been diagnosed with psoriatic disease (a skin and/or joint condition related to psoriasis) for at least 6 months before signing the consent form - You are between 18 and 75 years old - You are of Chinese ethnicity - You have moderate to severe psoriasis, based on a s...

**Who might be able to join this trial:** - People aged between 18 and 80 years old - People who have been diagnosed with psoriatic arthritis (PsA) for at least 6 months before joining, and who meet a standard set of classification criteria for PsA at the screening visit - People whose psoriatic arthritis has not resp...

**Who might be able to join this trial:** - You have had stable plaque psoriasis for 6 months or longer before the screening visit. - Your psoriasis is rated as moderate to severe based on three measurements taken at your screening visit and first study day: a skin scoring system called PASI (score of 12 or higher), a...

**Who might be able to join this trial:** - People who have signed a consent form before any study procedures begin. - People aged 18 or older, regardless of race or ethnicity. - People whose body mass index (a measure of body weight relative to height) falls between 18.0 and 40.0 at the screening visit. - People who...

Who might be able to join this trial: - Adults aged 18 or older who have been diagnosed with chronic plaque-type psoriasis - People whose psoriasis meets at least one of the following: a disease severity score (called PASI) above 6, psoriasis affecting the scalp, or psoriasis affecting the nails - People who show signs...

Who might be able to join this trial: - Adults who are already receiving regular care at one of the trial sites, or who have been separately invited to take part in the study. - People who have read the study information and signed a consent form agreeing to participate. Who may not be able to join: - People who have...

**Who might be able to join this trial:** - You are 18 years old or older and are being treated by a specialist for either Crohn's disease or plaque psoriasis. - You have been treated with the original (reference) version of the medication Ustekinumab for at least 6 months before joining the study. - Your condition has...

Who might be able to join this trial: - You have been diagnosed with one of the following conditions: juvenile idiopathic arthritis, rheumatoid arthritis, seronegative/psoriatic/undifferentiated arthritis, lupus (systemic lupus erythematosus), or diffuse systemic sclerosis, confirmed using standard medical guidelines (...

**Who might be able to join this trial:** - You have a close family member (such as a parent, sibling, or child) who has been diagnosed with Inflammatory Bowel Disease (IBD) - You have been diagnosed with an autoimmune disease (a condition where the immune system mistakenly attacks the body) - You have a digestive diso...

**Who might be able to join this trial:** - People who have signed and dated a consent form before any trial-related procedures begin. - People aged 18 or older at the time of signing the consent form. - People who, in the investigator's assessment, are able to attend clinic visits and follow the trial's requirements....

**Who might be able to join this trial:** *This trial has three groups. A person may be considered for one of the following:* **Group 1 – People who took deucravacitinib (a psoriasis medication) during pregnancy:** - People who are currently pregnant at the time of enrolment - People who have been diagnosed with psor...

Who might be able to join this trial: **For patients with skin conditions (general requirements):** - People who are able to understand and sign a written consent form before any study procedures begin - People who are male or non-pregnant female, aged 18 or older - People who are willing to avoid extensive washing, b...

Who might be able to join this trial: - You are between 18 and 65 years old (inclusive) at the time of your screening appointment - You are willing and able to give your informed consent before any study procedures take place - You have veins that can be accessed easily enough to allow blood samples to be taken Who ma...

**Who might be able to join this trial:** - People aged 18 years or older - People with fragile or brittle nails - People with a type of nail fungal infection called distal subungual onychomycosis (a fungal infection starting at the tip of the nail) - People with nail psoriasis that affects no more than 75% of the nail...

**Who might be able to join this trial:** *For the single-dose part of the study (SAD):* - You are a healthy adult between 18 and 45 years old - You meet the weight requirements: men must weigh at least 50 kg and women at least 45 kg, and everyone must weigh 110 kg or less, with a BMI between 18 and 28 - Your general...

Who might be able to join this trial: **For healthy volunteers:** - Men and women between 18 and 55 years old at the time of the screening visit - People with a body mass index (BMI) between 18.5 and 28, and a body weight of at least 50 kg for men or at least 45 kg for women - People who are willing to take part volun...

**Who might be able to join this trial:** - People who have been confirmed by their treating doctor to have moderate-to-severe plaque psoriasis, with or without joint involvement, before enrolling in the study. - People for whom treatment with risankizumab is appropriate according to the official prescribing guidelines...

Who might be able to join this trial: - People who are willing to give their written agreement to take part after fully understanding what the trial involves - People aged 18 to 70 years (inclusive) of any gender - People who have been clinically diagnosed with chronic plaque psoriasis for at least 6 months before the...

**Who might be able to join this trial:** - You are willing to take part voluntarily, have read and signed a consent form, and agree to follow the study procedures - You have plaque psoriasis that your doctor considers suitable for systemic (whole-body) treatment, and your condition has been stable — with no major flar...

Who might be able to join this trial: - You have been diagnosed with a chronic inflammatory condition, specifically psoriasis (a skin condition), psoriatic arthritis (joint and skin condition), spondyloarthritis (a type of joint inflammation), or inflammatory bowel disease (such as Crohn's disease or ulcerative colitis...

**Who might be able to join this trial:** - People who have recently been diagnosed with chronic plaque psoriasis (a skin condition that causes raised, scaly patches). **Who may not be able to join:** - People with psoriasis who have used systemic treatments (medicines that work throughout the whole body) in the 3 mon...

Who might be able to join this trial: - You have been diagnosed with chronic plaque psoriasis by a skin specialist (dermatologist) - You have previously been treated with biologic or targeted synthetic medicines (between 1 and 10 different treatments) for psoriasis in the United Kingdom Who may not be able to join: -...

**Who might be able to join this trial:** - People with a psoriasis severity score (called a PASI score) of less than 10, meaning their psoriasis is considered mild - People who have been fully informed about the study and have agreed to take part by signing a consent form - People aged between 18 and 60 years old who...

**Who might be able to join this trial:** - People who are willing to take part in the study and sign a consent form agreeing to participate - Men and women who have been diagnosed with stable plaque psoriasis for 6 months or more, where "stable" means no major changes in the appearance or severity of the condition -...

**Who might be able to join this trial:** - You are 18 years old or older at the time of signing the consent form - You have been diagnosed with palmoplantar pustulosis (a skin condition causing painful blisters/pustules on the palms and soles) for at least 24 weeks before your first screening appointment - Your condi...

**Who might be able to join this trial:** - Adults aged 18 or older who have psoriasis and for whom a whole-body (systemic) treatment has been recommended by their doctor - People diagnosed with chronic stable plaque psoriasis (a long-term, steady form of psoriasis that causes raised, scaly patches on the skin) - Peopl...

**Who might be able to join this trial:** - People aged between 18 and 70 years, of any gender - People who weigh more than 40 kg and have a body mass index (BMI) between 18 and 40 (a measure of body weight relative to height) - People who have been diagnosed with plaque psoriasis (a skin condition causing scaly patche...

Who might be able to join this trial: - People who are 18 years of age or older - People who have moderate to severe psoriasis, meaning that before starting their current treatment, more than 10% of their body surface was affected, or their psoriasis severity score (PASI) was above 10 - People who already have dermatol...

**Who might be able to join this trial:** This trial has three separate groups, each with their own criteria: **Group 1 – Hidradenitis suppurativa (a skin condition causing painful lumps):** - Adults aged 18 or older who have a moderate to severe form of this condition and are already receiving, or will be receiving,...

**Who might be able to join this trial:** - You have been diagnosed with chronic plaque psoriasis for at least 6 months before the screening visit. - Your psoriasis has been stable — meaning no major flare-ups or changes in how it looks — for at least 6 months before screening. - Your psoriasis is considered moderate...

**Who might be able to join this trial:** - People who have agreed to take part voluntarily and have signed a consent form - People aged 18 to 70 years old (male or female) - People who have had plaque psoriasis for at least 6 months before the start of the study - People whose psoriasis scores meet all three of the f...

Who might be able to join this trial: - People who have moderate to severe plaque psoriasis - People who started treatment with the medication deucravacitinib (taken on its own, not combined with other treatments) between 4 and 8 weeks before joining, as part of their normal medical care and in line with the reimbursem...

**Who might be able to join this trial:** - People who are able to give signed consent and follow the study rules as outlined in the study documents - Healthy men or women aged 18 to 55 years (inclusive) at the time of signing the consent form - People who smoke 10 or fewer cigarettes per week within the 3 months befo...

**Who might be able to join this trial:** - Adults between 18 and 70 years old, of any gender - People whose psoriasis covers a significant area of the body or is rated as moderate to severe using a standard scoring tool (confirm with trial site for exact score details) - People who have had plaque psoriasis for at lea...

Who might be able to join this trial: - People who are male or female and between 12 and 18 years old - People who have been diagnosed with plaque psoriasis and have had psoriasis for at least 6 months - People whose psoriasis has been considered suitable for light-based treatment (phototherapy) and/or medicines that w...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with palmoplantar pustulosis (PPP) through clinical assessment or laboratory/tissue testing - People for whom at least one standard whole-body (systemic) treatment has not worked well enough, or who were una...

Who might be able to join this trial: - Women who have Class I obesity (a body mass index in a range that a doctor can confirm) - People diagnosed with chronic plaque psoriasis (a long-term skin condition causing raised, scaly patches) - People diagnosed with polycystic ovarian syndrome (a hormonal condition affecting...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with plaque psoriasis for more than 6 months - People whose plaque psoriasis is considered moderate-to-severe, meaning it covers at least 10% of the body surface area, scores 12 or higher on a standard sever...

**Who might be able to join this trial:** - People aged 18 to 75 years old at the time of screening, of any gender - People who have been diagnosed with Generalized Pustular Psoriasis (GPP) based on specific criteria set by a 2017 international medical expert group (ERASPEN) - People who are currently experiencing an...

Who might be able to join this trial: - People who have recently been diagnosed with psoriasis, or who have not received any treatment for it in at least the last 6 months. - People of any age and any gender may be considered. Who may not be able to join: - People who are currently pregnant or breastfeeding. - People...

**Who might be able to join this trial:** - People who are willing to take part voluntarily, have read and understood what the trial involves, and have signed a consent form agreeing to follow the study procedures - People aged 18 to 70 years old (inclusive) at the time of signing the consent form, of any gender - Peo...

**Who might be able to join this trial:** - You are between 18 and 60 years old (any gender) - You have been diagnosed with moderate to severe plaque psoriasis, with a disease severity score of 10 or higher (measured by a standard psoriasis rating scale) - You have not taken any systemic (whole-body) treatments for you...

Who might be able to join this trial: - People who are between 18 and 65 years old (inclusive), of any sex - People with a Body Mass Index (a measure of body weight relative to height) above 18 and below 40 - People where plaque psoriasis covers at least 10% of the body surface area - People with a PASI score of 12 or...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with moderate-to-severe chronic plaque psoriasis covering at least 3% of your body surface area, and your skin tone falls into a medium to darker range on a standard skin color scale (Fitzpatrick type III or above) -...

**Who might be able to join this trial:** - Adults aged 18 or older at the time of joining the trial - People who have been diagnosed with plaque psoriasis of a certain severity and coverage across the body (confirm with trial site for specific measurements) - People with a body mass index (BMI) of 25 or higher, meanin...

**Who might be able to join this trial:** - People aged 18 to 70 years (inclusive) with a body mass index (BMI) of 18 or above - People who have been diagnosed with Psoriatic Arthritis (PsA) for at least 3 months before the screening visit, and who meet a specific set of recognised classification criteria for PsA at s...

**Who might be able to join this trial:** - You have been diagnosed with plaque psoriasis affecting your skin, scalp, or nails - You have not received any treatment for psoriasis for at least 4 weeks before the study starts - Your psoriasis is mild to moderate, meaning it covers no more than 10% of your body surface ar...

Who might be able to join this trial: - You are between 18 and 70 years old (any gender, race, or ethnic background) - You have been diagnosed with stable plaque psoriasis and have at least two affected skin areas that can be assessed during the trial - If you are a woman who could become pregnant, you must be using a...

Who might be able to join this trial: - Adults who are receiving the medication guselkumab to treat psoriasis affecting the skin. - People whose guselkumab doses are given more than 9 weeks apart. Who may not be able to join: - People who are receiving guselkumab mainly to treat joint problems (such as psoriatic arthr...

Who might be able to join this trial: - Adults between the ages of 18 and 60 years old - People with moderate to severe psoriasis, based on skin assessment scores measuring how much of the body is affected and how severely - People who also have moderate to severe depression and/or moderate to severe anxiety, as measur...

Who might be able to join this trial: - People who took part in the previous related trial and have signed a consent form agreeing to move into this follow-on stage. - People who fully completed the previous related trial. - Women who could become pregnant must have had a negative pregnancy test at the start of this st...

Who might be able to join this trial: - You are 18 years old or older at the time of signing up for the study. - A dermatologist (skin doctor) has confirmed you have stable psoriasis that you have had for at least 6 months. - You have other health conditions related to your psoriasis, such as psoriatic arthritis, as lo...

Who might be able to join this trial: - You are 18 years old or older, but younger than 80 years old - You have been diagnosed with plaque psoriasis for more than 6 months - Your psoriasis covers at least 10% of your body surface area, has a severity score of 12 or higher on the PASI scale, and rates at least 3 out of...

Who might be able to join this trial: - People who are 18 years of age or older - People who do not have severe joint deformity in the knuckle joints of the hand - People who have active joint disease, meaning at least one joint that is tender and at least one joint that is swollen, despite having taken anti-inflammato...

Who might be able to join this trial: - People who have been diagnosed with plaque psoriasis and have not had any significant flare-ups of their condition for at least 6 months before signing the consent form - People whose plaque psoriasis is considered moderate to severe, based on three specific medical measurements:...

**Who might be able to join this trial:** - You are between 18 and 75 years old (any gender) - You have been diagnosed with a specific skin condition called Palmoplantar Pustulosis (PPP) for at least 6 months, confirmed by recognised medical guidelines - Your PPP is considered moderate to severe, based on specific scor...

Who might be able to join this trial: - You have been diagnosed with plaque psoriasis (with or without joint inflammation related to psoriasis) before the study treatment begins - At least 10% of your total body surface area is affected by psoriasis at both your screening and baseline appointments - Your psoriasis seve...

Who might be able to join this trial: - The patient (or their guardian) is able to agree to take part in the study - The patient is under 19 years old - The patient has been diagnosed with Inflammatory Bowel Disease (IBD), which is a condition causing long-term inflammation in the digestive system (such as Crohn's dise...

**Who might be able to join this trial:** - People who have been formally diagnosed with psoriatic arthritis by a rheumatologist, using a recognised set of classification criteria called CASPAR - People who are starting a medication called guselkumab as their first, second, third, or fourth targeted treatment for psori...

**Who might be able to join this trial:** - People who have been diagnosed with plaque-type psoriasis (with or without psoriatic arthritis) for at least 6 months before the study begins — with or without joint involvement. - People whose psoriasis is considered moderate to severe, based on standard skin assessment sco...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with rheumatoid arthritis (a condition where the immune system attacks the joints, causing pain and swelling) - You have been diagnosed with psoriatic arthritis (a type of joint inflammation linked to the skin conditi...

Who might be able to join this trial: - People aged 18 to 65 years, of any gender - People who have been diagnosed with palmoplantar pustulosis (a skin condition causing pustules on the hands and feet) based on clinical examination and/or skin tissue testing - People who have already tried at least one standard systemi...

Who might be able to join this trial: - People who have been diagnosed with moderate-to-severe plaque psoriasis - People who are willing and able to sign a consent form allowing the trial site to verify their health information as required by local rules - People who can read, understand, and fill in patient questionna...

Who might be able to join this trial: - You have been diagnosed with psoriasis - You are between 18 and 65 years old - Both men and women are welcome to participate - You are willing to sign a consent form agreeing to take part in the study - You are currently experiencing emotional or mental distress related to your c...

**Who might be able to join this trial:** - People who are at least 18 years old at the time of joining the study - People who have been assessed by their doctor as having moderate to severe plaque psoriasis, based on a standard clinical assessment score of 3 or 4 - People who are starting a new qualifying medication...

Who might be able to join this trial: - A signed general consent form, or an equivalent document, has been completed. - A confirmed diagnosis of psoriasis has been established. Who may not be able to join: - People who are unable to provide informed consent. - People whose diagnosis records are unclear or ambiguous....

Who might be able to join this trial: - People who are at least 18 years old at the time of joining the study - People who have been diagnosed with moderate to severe plaque psoriasis, confirmed by a doctor's assessment at the time of enrollment (a specific score of 3 or 4 on a standard scale used by the investigating...

**Who might be able to join this trial:** - People aged 18 to 75 years old at the time of signing consent to participate - People who have been diagnosed with plaque psoriasis for at least 6 months before the screening visit - People whose psoriasis covers a significant portion of the body and is rated as moderate to s...