Ovarian Cancer Trial, Recruiting NCT05429970 Sponsor: Memorial Sloan Kettering Cancer Center Condition: Ovarian Cancer
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Ovarian Cancer Trial, Recruiting

NCT05429970
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with advanced (stage II–IV) ovarian, fallopian tube, or peritoneal cancer, based on scans, a blood test called CA125, and a doctor's assessment
  • You are scheduled to have open abdominal (exploratory) surgery to remove as much of the cancer as possible
  • Your surgery is planned at least 10 days from now, allowing enough time to take the study medications for 7 days before the operation
  • You are 18 years of age or older
  • Your general fitness for surgery has been rated at a low to moderate level by your medical team (ASA score 1–3) (confirm with trial site)
  • You are able to understand what the study involves, follow the study plan, and give your written consent to participate

Who may not be able to join:

  • You are already taking a beta-blocker or COX inhibitor medication on a regular basis
  • You have a medical condition that makes taking beta-blocker medication unsafe for you, such as asthma, certain heart rhythm problems, heart failure, or certain circulation problems (confirm with trial site)
  • You have a medical condition that makes taking a COX2 inhibitor medication unsafe, such as kidney problems, significant liver disease, a stomach ulcer, or you are currently taking blood-thinning tablets
  • You have a condition that means you cannot safely have a type of pain relief called an epidural
  • You have a long-term autoimmune disease
  • You currently have an active infection
  • You are pregnant
  • Your surgery is planned as a minimally invasive (keyhole) procedure rather than open surgery
  • You are already taking part in another clinical trial that could affect this study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Kara Long Roche, MD, Memorial Sloan Kettering Cancer Center

Phone: 212-639-7043

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
17 June 2022
Est. completion
17 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of participants successfully completing over 80% of the bundled interventions

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov