Prostate Cancer Trial, Recruiting NCT05438563 Sponsor: Mayo Clinic Condition: Prostate Cancer
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Prostate Cancer Trial, Recruiting

NCT05438563
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are male and between 45 and 80 years old, with an expected life expectancy of more than 10 years
  • You have been diagnosed with intermediate-risk prostate cancer, confirmed by a biopsy, falling into specific risk categories (confirm with trial site)
  • Your cancer has not spread beyond the prostate or to nearby lymph nodes or other parts of the body
  • Your biopsy was done using specific methods with a minimum number of tissue samples taken, and the results are from within the last 12 months, with at least 6 weeks between your biopsy and your first study visit
  • Your PSA blood test result was 20 ng/mL or below, taken within the last 3 months
  • You have not yet received any treatment for your prostate cancer
  • The area of the prostate planned for treatment is within a certain size limit based on a recent MRI scan taken within the last 6 months

Who may not be able to join:

  • You are unable to have an MRI scan or be put under general anaesthesia
  • Your tumour is located either too far from or too close to the tube that carries urine through the prostate (confirm with trial site)
  • You have calcium deposits larger than 3 mm in the prostate area that could block treatment, as shown on a scan taken within the last year (this may be reviewed further by the study team)
  • You currently have an unresolved urinary tract infection or prostate infection
  • You have a history of rectal inflammation, bladder stones, blood in the urine, sudden inability to urinate, or a severely impaired bladder caused by nerve problems
  • You have an artificial urinary sphincter, a penile implant, or an implant inside the prostate
  • Your life expectancy is less than 10 years
  • You have been assessed as not being a suitable candidate for prostate removal surgery
  • You are unable or unwilling to give your formal consent to take part in the study
  • You have a history of scarring or narrowing in the back passage, rectum, or urethra, or any other physical issue that would make it difficult to insert the equipment used in this procedure

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: David A Woodrum, MD, PhD, Mayo Clinic in Rochester

Phone: 855-776-0015

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
6 April 2022
Est. completion
7 March 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Proportion of patients free from treatment failure; Proportion of patients who maintain both urinary continence and erectile potency

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov