Crohn's Disease and Colitis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older at the time of signing the consent form
- People who have been diagnosed with ulcerative colitis (UC) for at least 3 months
- People whose UC is considered moderate to severe, based on a standard scoring system called the Mayo Score (score of 6 or higher)
- People whose UC is considered moderate to severe based on camera examination of the bowel (score of 2 or higher on that exam)
- People for whom a doctor has decided it is appropriate to start a biological therapy or small molecule treatment (such as anti-TNF, anti-IL12/23, anti-integrin, or JAK-inhibitor medicines)
- People taking corticosteroids (steroid tablets) at a stable dose for at least 3 weeks before the study starts, at a dose no higher than 20mg of prednisone per day
- People who are already scheduled for a bowel camera examination (endoscopy) as part of their usual care
- People who are able to follow the study procedures
- People who are covered by a social security plan
- People who have been informed about the study and are able to sign a consent form
Who may not be able to join:
- People diagnosed with certain other types of colitis, including indeterminate colitis, microscopic colitis, ischaemic colitis, infectious colitis, or radiation colitis
- People for whom a bowel camera examination (endoscopy) is not safe, or who have had a serious complication during a previous endoscopy
- People with bleeding disorders
- People who need surgery for their UC
- People who have used rectal treatments such as enemas or suppositories within 2 weeks before the study starts
- People who have taken more than 20mg of prednisone (steroids) within the 3 weeks before the study starts
- People with anaemia (low red blood cell levels, specifically haemoglobin below 10 g/dl) at the start of the study
- People who the study doctor considers unsuitable for any other reason
- Women who are pregnant, in labour, or breastfeeding
- People under 18 years of age
- Adults who are under legal guardianship or protection
- Adults who are unable to give consent and are not under legal protection
- People who are detained by a judicial or administrative decision, or who are under certain forms of compulsory psychiatric care
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Stefan MD SCHREIBER, PhD, Christian Albrechts Universität
Phone: 0383153661
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
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Trial details
Where this trial is recruiting
Primary endpoints
The percentage of subjects who achieve clinical response at week 14.; The percentage of subjects who achieve deep clinical remission at week 14.; The percentage of subjects who achieve deep clinical remission at week 26.; The percentage of subjects who achieve deep clinical remission at week 52.; The percentage of subjects who achieve mucosal healing at week 14.; The percentage of subjects who achieve mucosal healing at week 52.; The percentage of subjects who achieve symptomatic remission at week 14.; The percentage of subjects who achieve symptomatic remission at week 26.; The percentage of...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.