Alzheimer's Disease Trial, Recruiting NCT05460143 Sponsor: University of Cambridge Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Recruiting

NCT05460143
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with probable Lewy Body Dementia, Alzheimer's Disease, or Mild Cognitive Impairment (either Lewy Body or Alzheimer's type) — OR you are cognitively normal for your age and education level
  • You scored above 26 on a standard memory and thinking test called the MMSE (this applies to those joining as a healthy volunteer)
  • You have a good understanding of the English language
  • You have a carer or family member who can be present during testing sessions (this applies to those joining as a patient, not a healthy volunteer)

Who may not be able to join:

  • Your dementia is considered severe, or you scored below 12 on the MMSE memory and thinking test
  • You have a condition that affects how your body processes substances or regulates blood flow, such as a metabolic or breathing disorder
  • You have a significant inflammatory or immune system condition, such as rheumatoid arthritis or lupus, or you regularly take steroid tablets by mouth
  • You have a significant mental health or psychiatric disorder
  • Your memory or thinking problems are caused by something other than Alzheimer's or Lewy Body disease, such as a head injury, vascular dementia, or fronto-temporal dementia
  • You have a history of heavy or excessive drug or alcohol use
  • You have anything in or on your body that is not safe in an MRI scanner, such as a pacemaker (this applies to patients having an MRI scan) (confirm with trial site)
  • You are considered to have a level of obesity that may affect MRI scanning (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Gemma Bale, PhD, University of Cambridge

Phone: 07462064164

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Cambridge
Registry
ClinicalTrials.gov
Start date
1 May 2023
Est. completion
1 September 2025

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Brain oxygenation; Brain metabolism; Cognitive behavioural data

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov