Phase 2 Lymphoma Trial, Recruiting NCT05463263 Sponsor: Step Pharma, SAS Condition: Lymphoma
Back to Lymphoma

Phase 2 Lymphoma Trial, Recruiting

NCT05463263
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have signed and agreed to take part, and are able to follow the study procedures.
  • You are 18 years of age or older.
  • You have been diagnosed with B cell or T cell lymphoma (confirmed by a tissue sample) that has come back or stopped responding to treatment.
  • You have already tried at least 2 different treatments for your lymphoma, and there are no other known treatments that are likely to help.
  • Your lymphoma can be measured using standard medical imaging or assessment tools.
  • Your general health and ability to carry out daily activities meets a certain minimum level (confirm with trial site).
  • Your doctor expects you to live for more than 3 months.
  • Your bone marrow, liver, kidneys, and blood clotting are all working well enough.
  • Any side effects from previous cancer treatments have mostly cleared up before joining the trial (hair loss is an exception).

Who may not be able to join:

  • You are pregnant, breastfeeding, or unwilling to use contraception during the study (applies to both women who could become pregnant and men).
  • Your lymphoma has spread to the brain or spinal fluid.
  • You have had another active cancer within the last 2 years.
  • You have only had radiation or surgery to treat your lymphoma with no other areas of measurable disease, or you have had radiation or surgery within 2 weeks of starting the trial.
  • You have received other cancer treatments, antibody therapies, or experimental treatments within 4 weeks before joining (or within a certain time based on the specific drug used).
  • You have another serious illness that is not currently under control.
  • You have a weakened immune system that puts you at higher risk of certain infections, or you have had a serious infection of that type in the last 12 months.
  • You have an active or long-term hepatitis B infection, or an active hepatitis C infection.
  • You have received a live vaccine within 30 days before joining the trial, or plan to during the study.
  • Your heart's electrical activity shows a certain abnormality on an ECG test (confirm with trial site).
  • You have received a COVID-19 vaccine within 3 weeks before starting the study drug.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 2 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Step Pharma, SAS
Registry
ClinicalTrials.gov
Start date
3 August 2022
Est. completion
1 December 2026

Where this trial is recruiting

🇫🇷 France 🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Safety and Tolerability (Phase 1 / Dose Escalation); Objective Response Rate (ORR) (Phase 2 / Dose Expansion)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov