Macular Degeneration Trial, Recruiting NCT05465252 Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Condition: Macular Degeneration
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Macular Degeneration Trial, Recruiting

NCT05465252
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are an adult who has been diagnosed with early or intermediate stage dry age-related macular degeneration (AMD), confirmed by eye imaging photos.
  • You are willing to stop taking omega-3 fatty acid, choline, or astaxanthin supplements during the trial.
  • You are willing to sign a consent form and attend follow-up appointments for at least 3 months.

Who may not be able to join:

  • You have an eye condition (other than AMD) that would interfere with eye examination results.
  • You have a specific form of AMD involving abnormal blood vessel growth (CNV), advanced AMD with areas of tissue loss (geographic atrophy), or severe short-sightedness in either eye.
  • You have had eye surgery that could affect how AMD is assessed (confirm with trial site).
  • You take medications long-term that are known to be harmful to the retina or nerves of the eye.
  • You have taken lutein, zeaxanthin, DHA, or EPA supplements recently, unless you have stopped taking them for at least 8 weeks before joining the trial.
  • Your eye pressure is higher than 26 mmHg.
  • You have had cataract surgery within the last 3 months.
  • You have a serious long-term illness affecting your overall health.
  • You have a condition, such as a memory or thinking disorder, that may make it difficult to follow the trial schedule reliably.
  • You are currently taking part in another clinical trial that would conflict with this one.
  • You are currently taking anti-angiogenesis drugs (medicines that block blood vessel growth) to treat cancer.
  • There may be other reasons that make you unsuitable, as decided by the trial team (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Xiaodong Sun, PHD, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Phone: +86 18017317575

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Registry
ClinicalTrials.gov
Start date
17 October 2025
Est. completion
1 March 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Change in Macular Drusen Volume

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov