Phase 2 Breast Cancer Trial, Recruiting NCT05475678 Sponsor: Zhenzhen Liu Condition: Breast Cancer
Back to Breast Cancer

Phase 2 Breast Cancer Trial, Recruiting

NCT05475678
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged between 18 and 70 years old
  • People with a certain stage of breast cancer (ranging from early to more locally advanced stages), or a smaller tumour that has spread to the lymph nodes under the arm, confirmed by clinical and laboratory testing
  • People whose breast cancer has been confirmed by biopsy to be "triple negative," meaning the cancer does not respond to oestrogen, progesterone, or a protein called HER-2
  • People who have at least one tumour that can be measured by ultrasound, mammogram, or MRI scan within one month before joining the trial
  • People whose organ and bone marrow function tests, taken within one month before starting chemotherapy, show no reasons to avoid chemotherapy
  • People whose heart pumping function (measured by a heart ultrasound) is at least 55%
  • Women of childbearing age who have a negative blood pregnancy test taken within 14 days before joining the trial
  • People who have a good general health and activity level (rated 0 or 1 on a standard medical scale called the ECOG score, meaning fully active or able to carry out light work)
  • People who have read and signed a consent form agreeing to take part

Who may not be able to join:

  • People whose breast cancer has already spread to other parts of the body
  • People who have already received chemotherapy, hormone therapy, targeted therapy, or radiation therapy for this breast cancer
  • People who have a second, separate cancer (other than certain well-treated skin cancers)
  • People who have previously been treated with a type of immune therapy that targets proteins called PD-1, PD-L1, or PD-L2, or any other immunotherapy
  • People who have been diagnosed with an immune system deficiency disease or an autoimmune disease (where the immune system attacks the body)
  • People who have severe lung or heart disease
  • People who have active hepatitis B or hepatitis C infection
  • People who have had an organ transplant or bone marrow transplant in the past
  • Women who are pregnant or breastfeeding
  • People whose overall medical condition leads the trial doctors to consider chemotherapy unsafe for them

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 6 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Zhenzhen Liu, Study Principal Investigator

Phone: 13603862755

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Zhenzhen Liu
Registry
ClinicalTrials.gov
Start date
20 December 2022
Est. completion
31 May 2025

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Pathological complete response rate (pCR rate)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov