Osteoarthritis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have hip pain rated between 4 and 8 out of 10 on a pain scale, based on the past week
• People who have imaging evidence of hip osteoarthritis, either on X-ray (early to moderate stage) or on MRI (showing early cartilage or joint rim changes, without recent injury)
• People where only one hip is affected
• People whose recent blood test shows a haemoglobin level above 11 g/dl (a measure of healthy red blood cells)
• People whose recent blood test shows a platelet count above 150,000 per mm³ (platelets help blood clot)
• People whose blood tests show negative results for Hepatitis B, Hepatitis C, and HIV
• People whose recent heart tracing (ECG) shows no significant concerns
• People who are willing and able to attend follow-up appointments throughout the trial
• People who have read and signed the trial's informed consent form

Who may not be able to join:

• People who are not able to give their own consent to participate
• People who have had an injection into the affected joint within the past 6 months
• People who have had surgery on the affected leg within the past 12 months
• People who have been diagnosed with cancer
• People who have a rheumatic disease (such as rheumatoid arthritis)
• People with diabetes that is not well controlled
• People with blood or clotting disorders
• People who take blood-thinning or anti-clotting medication that cannot be safely stopped for at least 3 days before a blood sample is taken
• People with thyroid conditions that are not well controlled
• People with a history of heavy alcohol use, or misuse of drugs or medications
• People with a Body Mass Index (BMI) over 30
• People who have taken anti-inflammatory pain medications (such as ibuprofen) in the 3 days before the blood draw
• People with heart or cardiovascular conditions for whom having 300 ml of blood taken would not be safe
• People whose recent blood test shows haemoglobin below 11 g/dl or platelets below 150,000 per mm³
• People who test positive for Hepatitis B, Hepatitis C, or HIV
• People who are pregnant or are women of childbearing potential (confirm with trial site)
• People whose hip pain is rated lower than 4 or higher than 8 out of 10 on the pain scale
• People who have other specific hip conditions, such as severe joint deformity, abnormal bone structure, collapse of the joint, or hip problems resulting from a childhood bone disease or bone tissue death
• People who have previously had major hip surgery, such as bone-repositioning surgery or surgery to correct a hip impingement condition

Important: Always verify eligibility with the trial site directly before applying.