Breast Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People diagnosed with a specific type of breast cancer called invasive ductal carcinoma that is estrogen receptor positive and HER-2 negative, is a lower grade (grade 1 or 2), has a limited amount of a related pre-cancer component (less than 25%), and measures 2 cm or smaller with no spread to lymph nodes or other parts of the body.
• If a pre-cancerous area called DCIS is found in the biopsy, it must make up less than 25% of the tumor and must be directly connected to the main cancer, not appearing as a separate area.
• For certain tumour sizes and scores, a genetic test called an Oncotype DX test will be done, and the result must be below 26 to be eligible for those cases (confirm with trial site for details on which tumours require this).
• People aged 50 or older.
• People whose lymph nodes under the arm on the same side as the cancer have been assessed and found to be cancer-free, through one of three methods: an ultrasound scan, a sentinel lymph node biopsy, or a needle biopsy of a lymph node, with no other concerns about spread to lymph nodes.
• People who are able to understand and are willing to sign a formal consent document approved by an ethics review board.

Who may not be able to join:

• People for whom chemotherapy before surgery has been recommended.
• People with a previous history of breast cancer.
• People who have had breast implants or augmentation.
• People with a known allergy to local anaesthetics.
• People who are pregnant or breastfeeding; women who could potentially become pregnant must have a negative pregnancy test within 14 days of entering the study.
• People whose cancer has grown into the skin or the chest wall.

Important: Always verify eligibility with the trial site directly before applying.