Oesophageal Cancer Trial, Recruiting NCT05530343 Sponsor: University of Colorado, Denver Condition: Oesophageal Cancer
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Oesophageal Cancer Trial, Recruiting

NCT05530343
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For people already diagnosed with Barrett's esophagus (a condition affecting the lining of the food pipe) who are attending a routine check-up scope:

  • People attending a routine monitoring endoscopy (camera procedure) for Barrett's esophagus with no current abnormal cell changes, including those who previously had minor cell changes but whose most recent endoscopy showed no abnormalities
  • People whose Barrett's esophagus affects at least a minimal measurable length of the food pipe
  • People who speak English or Spanish
  • People who are able to understand and complete a consent form
  • People aged 18 to 89 years
  • People with a life expectancy of at least 2 years

For people attending an endoscopy to check whether they have Barrett's esophagus for the first time:

  • People having an endoscopy to find out if they have Barrett's esophagus
  • People whose Barrett's esophagus (if found) affects at least a minimal measurable length of the food pipe
  • People who speak English or Spanish
  • People who are able to understand and complete a consent form
  • People aged 18 to 89 years
  • People with a life expectancy of at least 2 years

Who may not be able to join:

For people attending routine monitoring endoscopy:

  • People who are having their endoscopy to assess or manage previously diagnosed abnormal or cancerous cell changes in the food pipe
  • People with active, significant inflammation and damage to the food pipe lining (graded B or higher on a standard medical scale)
  • People who have swollen veins in the food pipe (esophageal varices)
  • People who have previously had a procedure to remove or destroy abnormal tissue in the food pipe
  • People who have previously had surgery on the food pipe or stomach, unless it was a straightforward anti-reflux procedure (fundoplication) with no complications
  • People who are pregnant

For people attending a first-time screening endoscopy:

  • People who are having their endoscopy to assess or manage previously diagnosed abnormal or cancerous cell changes in the food pipe
  • People with active, significant inflammation and damage to the food pipe lining (graded B or higher on a standard medical scale)
  • People who have swollen veins in the food pipe (esophageal varices)
  • People who have previously had surgery on the food pipe or stomach, unless it was a straightforward anti-reflux procedure (fundoplication) with no complications
  • People who are pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Sachin Wani, MD, University of Colorado, Denver

Phone: 303-724-0432

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
3 October 2022
Est. completion
1 June 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Diagnostic yield of dysplasia (Surveillance population only); Diagnostic yield of intestinal metaplasia (Screening population only)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov