Phase 2 Prostate Cancer Trial, Recruiting NCT05568550 Sponsor: Zin W Myint Condition: Prostate Cancer
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Phase 2 Prostate Cancer Trial, Recruiting

NCT05568550
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Male patients who have been diagnosed with prostate cancer (specifically a type called adenocarcinoma), confirmed through a tissue test
  • People whose prostate cancer is classified as high-risk or very high-risk according to standard medical guidelines (called NCCN guidelines)
  • People who are generally well enough to carry out daily activities with no or minimal limitations (confirm with trial site)
  • People whose cancer may have spread to nearby lymph nodes in the surrounding region
  • People who are willing to use contraception throughout the treatment period and for at least 120 days after the last dose, and who agree not to donate sperm during this time
  • People who are able to understand and willing to sign a written consent form
  • People whose organs (such as kidneys, liver, and bone marrow) are functioning at an adequate level
  • People who have previously received hormone-reducing medication for prostate cancer, provided that treatment started no more than 90 days before registering for the trial
  • People with a history of heart disease or prior treatment with medications that can affect the heart will need a heart health assessment before joining (confirm with trial site)

Who may not be able to join:

  • People who have continuously received certain hormone-blocking treatments (such as Lupron or Degarelix) for prostate cancer for more than 90 days before enrolling in the trial
  • People who have previously had radiation therapy to the prostate or to the pelvic lymph nodes
  • People who have previously had major surgery, such as bowel reconnection surgery or full bladder removal
  • People with a history of a condition called ulcerative proctitis (inflammation of the lower bowel lining)
  • People who have had another active cancer within the last 2 years
  • People who have received any other systemic cancer treatment, including experimental treatments, within 4 weeks before joining the trial
  • People whose prostate cancer has spread to distant parts of the body beyond the local or regional area (known as M1 disease)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Zin W Myint, MD, University of Kentucky

Phone: 859-257-3379

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Zin W Myint
Registry
ClinicalTrials.gov
Start date
27 July 2023
Est. completion
2 December 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Clinical Response Rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov