Hearing Loss Trial, Recruiting NCT05572073 Sponsor: Akouos, Inc. Condition: Hearing Loss
Back to Hearing Loss

Hearing Loss Trial, Recruiting

NCT05572073
Recruiting Not Applicable 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have hearing loss in both ears caused by a problem with how the inner ear or hearing nerve sends signals to the brain (including a specific type called auditory neuropathy)
  • People who have a change (mutation) in the otoferlin gene, which is linked to this type of hearing loss
  • People who are willing and able to follow all study requirements and have completed the consent process

For the active monitoring part of the study, there is one extra requirement:

  • People who have specific hearing test results — one type of test showing a response (OAEs or cochlear microphonics) while another type (ABR) shows absent or abnormal results — in at least one ear that does not have a cochlear implant, tested within the past 12 months or at the first study visit

Who may not be able to join:

  • People (or their legal representatives) who are unable or unwilling to follow all study requirements
  • People who have a problem with the structure or size of the hearing nerve itself (cochlear nerve deficiency or dysplasia)

For the active monitoring part of the study, there are additional reasons a person may not be eligible:

  • People who have cochlear implants in both ears, or who are planning to receive them in the next 6 months
  • People who have a middle ear implant or a brainstem implant, or who are planning to receive one within the next 6 months
  • People who have any condition that the study doctor believes would prevent them from completing all follow-up visits or makes participation unsuitable (confirm with trial site)

Note: Eligibility is not based on sex, gender, race, or ethnicity.


Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Peter Marks, MD, Eli Lilly and Company

Phone: +1 857 410 1816

Australian sites

Murdoch Children's Research Institute, Parkville, Victoria

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Akouos, Inc.
Registry
ClinicalTrials.gov
Start date
14 July 2022
Est. completion
1 February 2029

Where this trial is recruiting

🇦🇺 Australia 🇩🇪 Germany 🇪🇸 Spain 🇹🇼 Taiwan Turkey (Türkiye) 🇬🇧 United Kingdom 🇺🇸 United States

1 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

ABR

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov