Hearing Loss

**Who might be able to join this trial:** - You have hearing loss in the ear to be implanted that is caused by a problem with sound conduction (such as in the ear canal or middle ear), with inner ear hearing ability still relatively intact (confirmed by a specific hearing test result) - You have total or near-total hea...

Who might be able to join this trial: - You meet the requirements set by the implant centre to receive a specific type of cochlear implant (Cochlear Nucleus CI512, CI422, CI522, or CI532) - You are 18 years old or older at the time of receiving the implant Who may not be able to join: - You have previously received a...

**Who might be able to join this trial:** - You are 18 years old or older - You have a type of hearing loss called conductive or mixed hearing loss in the ear to be treated, with bone hearing test results reaching a certain level of loss (confirm with trial site) - OR you have complete hearing loss in one ear (single-...

**Who might be able to join this trial:** - You have hearing loss in the ear to be treated that is either conductive (sound not reaching the inner ear properly) or mixed (a combination of types), with inner ear function within a certain range measured by a hearing test — OR you are deaf in one ear while the other ear...

**Who might be able to join this trial:** - You use a CE-approved Nucleus brand cochlear implant that allows you to understand spoken words without lip-reading. - You have been using your cochlear implant for at least three months. - You are 18 years of age or older at the time you enter the study. - You are fluent in...

**Who might be able to join this trial:** - You currently use a Nucleus cochlear implant that has been officially approved, and it helps you understand spoken words without lip-reading. - Children must be older than 5 years and under 18 years old when joining the study (available in Belgium only for children). - Adults...

**Who might be able to join this trial:** - You are 18 years old or older (there is no maximum age limit) - You have a specific type of cochlear implant (CIC4-based) with one of three particular electrode types, and you have had it for at least 6 months - You speak the language that will be used to test your hearing an...

**Who might be able to join this trial:** - People who are generally healthy males or females between 18 and 45 years old (inclusive) at the time of screening, as determined by the trial doctor based on medical history, lab results, vital signs, heart tracings, and a physical exam. - People who are willing and able to...

Who might be able to join this trial: - Babies and toddlers between 3 and 24 months old who have normal hearing and have completed a full hearing assessment showing no hearing loss - Babies and toddlers between 3 and 24 months old who have been found to have hearing loss during a hearing assessment, whose parents have...

**Who might be able to join this trial:** - People who have hearing loss in both ears caused by a problem with how the inner ear or hearing nerve sends signals to the brain (including a specific type called auditory neuropathy) - People who have a change (mutation) in the otoferlin gene, which is linked to this type of...

Who might be able to join this trial: **For audiologists:** - You are a qualified audiologist who meets the requirements for membership of Audiology Australia. - You have at least 1 year of experience working with children in hearing diagnosis, hearing aids, or cochlear implant services in Australia. - You are willing...

Who might be able to join this trial: - Adults aged 18 years or older. - People who currently use at least one hearing device, such as a hearing aid or cochlear implant. - People who are fluent speakers of the language used during the trial's hearing assessments, as determined by the trial investigator. - People who ar...

**Who might be able to join this trial:** - You are 60 years of age or older - You have mild-to-moderate hearing loss in both ears, based on a specific hearing test measuring how well you hear certain sound frequencies - You are not currently using any hearing aids, cochlear implants, or other devices to help you hear...

**Who might be able to join this trial:** - People aged 18 years or older - People who feel they have mild to moderate hearing difficulties or hearing loss - People who are comfortable using a smartphone and able to complete a self-fitting process through an app - People who are willing and able to give formal consent...

Who might be able to join this trial: **Group 1 – Children who were born with or developed hearing loss very early (from birth to age 5, receiving the device between 18 months and 5 years):** - Children with early hearing loss where brain scans (MRI and/or CT) show a specific inner ear or hearing nerve problem, such a...

**Who might be able to join this trial:** - People who have tinnitus (ringing or noise in the ears) in one ear only - People whose tinnitus severely impacts their daily life - Men or women aged 18 years or older - People whose tinnitus has been present for more than 1 year and has stayed the same during that time - Pe...

**Who might be able to join this trial:** - You have been diagnosed with Wolfram syndrome and have access to the internet. - You developed diabetes (high blood sugar) before the age of 16 AND/OR experienced vision loss due to optic nerve damage before the age of 16 (these are the main qualifying conditions). - You may...

**Who might be able to join this trial:** - You are 18 years old or older - You are any gender (male or female) - You have had ringing or noise in your ears (tinnitus) for 6 months or longer - You can understand and speak English well enough to describe sensations and fill out surveys - If the trial involves using a co...

Who might be able to join this trial: **For adults:** - People between 18 and 90 years old - People who do not have any neurological or psychiatric conditions - People who do not have significant cognitive difficulties and are able to understand and follow the study instructions - People who are motivated to take part...

**Who might be able to join this trial:** - You have previously had radiosurgery (a type of targeted radiation treatment) for a non-cancerous ear tumour called a vestibular schwannoma (also known as an acoustic neuroma) - You are interested in having a cochlear implant (a small electronic device surgically placed in th...

Who might be able to join this trial: - Adults aged 18 to 99 who are having a type of ear surgery called translabyrinthine vestibular schwannoma resection (a procedure to remove a non-cancerous tumour near the inner ear) - People who want hearing restoration through a cochlear implant (a small electronic device surgica...

**Who might be able to join this trial:** *Prospective Patient Group (joining before treatment):* - People who have been diagnosed with head and neck cancer - People whose medical team has decided their treatment will involve radiotherapy, with or without a chemotherapy drug called cisplatin *Retrospective Patient Gr...

"Who might be able to join this trial: - People who were diagnosed with diabetes before the age of 25, where the type was recorded as either type 1 or not yet determined. Who may not be able to join: - People who have already had autoantibody testing related to type 1 diabetes and received a positive result. (Autoanti...

Who might be able to join this trial: - You must be 18 years of age or older - Your surgeon and you have agreed that surgery to remove a vestibular schwannoma (a type of non-cancerous ear tumour) is the right treatment for you - You have given your written agreement to take part in the trial - You are covered by French...

**Who might be able to join this trial:** - You have tinnitus (ringing in the ears) that is at least moderately severe, based on a specific questionnaire score, and it is linked to blast or loud noise exposure, a head injury, or a concussion diagnosed by a healthcare provider - You are 18 years of age or older - You a...

Who might be able to join this trial: - You must be 18 years old or older - You must have been diagnosed with a condition called bilateral vestibulopathy, which means both of your inner ears have reduced ability to help control your balance and eye movements — this is confirmed through specific balance and eye movement...

**Who might be able to join this trial:** - You have been diagnosed with advanced non-small cell lung cancer (NSCLC) that cannot be removed by surgery or has spread to other parts of the body, confirmed by a lab test on a tissue sample - You are willing to provide a sample of your tumor tissue as required by the trial...

**Who might be able to join this trial:** *Adult Treatment Group:* - You have been diagnosed with Osteogenesis Imperfecta (OI) Type I (a condition affecting bone strength) - You have been diagnosed with at least mild hearing loss (confirmed by a hearing test) - You are 18 years of age or older - Your Vitamin D level i...

Who might be able to join this trial: - You are between 18 and 70 years old - You have been diagnosed with obstructive sleep apnea (a condition where breathing repeatedly stops during sleep) confirmed by a sleep study, with more than 15 breathing interruptions per hour - You have been diagnosed with sudden unexplained...

**Who might be able to join this trial:** - People aged 18 or older - People who are able to give informed consent to participate - People who speak English - People who fall into one of four hearing and tinnitus groups: - **Group 1:** Normal hearing in both ears and no tinnitus (tinnitus reported as "never" or "rare...

Who might be able to join this trial: - You are between 18 and 55 years old - You are covered by a social security system - You can understand spoken and written French - You have normal hearing, confirmed by standard hearing tests (tympanogram and audiogram) Who may not be able to join: - You currently have any heari...

**Who might be able to join this trial:** - People whose first language is English - People with normal vision, or vision that is corrected to normal with glasses or contact lenses (20/40 binocular vision or better, as measured by a standard eye chart) - People with a specific type and degree of hearing loss — sensorin...

**Who might be able to join this trial:** - You are between 18 and 75 years old - You have tinnitus (ringing in one or both ears) that is constant and non-pulsating, and does not involve balance problems — you may or may not also have hearing loss - Your tinnitus has not improved despite trying treatments - Your tinnit...

**Who might be able to join this trial:** **Group 1 (children aged 10–24 months):** - Children between 10 and 24 months old - Children whose family is registered with the social health insurance system, and whose parents agree to take part - Children who were born deaf with severe to profound hearing loss and are abou...

**Who might be able to join this trial:** - People who have inherited hearing loss that runs in their family in a specific pattern (called "autosomal dominant"), ideally confirmed by a genetic test - Family members of someone already enrolled in the trial who are known to have this type of inherited hearing loss - Fami...

**Who might be able to join this trial:** - You are 5 years old or older at the time of receiving the implant - You have severe to total hearing loss in one ear, with hearing test results showing a loss of 90 dB or greater in that ear - Your hearing loss in the ear to be implanted is caused by a problem with the inner...

Who might be able to join this trial: - Adults aged 18 or older who speak French - People who meet the medical criteria for receiving a cochlear implant (an electronic device surgically placed to help with hearing) - People whose cochlear implant has been inserted at a specific deep angle (greater than 450°) as measure...

Who might be able to join this trial: - You have been diagnosed with Usher syndrome type I, II, or III, either through genetic testing or through a clinical diagnosis that will later be confirmed by genetic testing - You are covered by health insurance - You (or your legal guardian, if applicable) have agreed to take p...

Who might be able to join this trial: - You have mild-to-moderate hearing loss - You live in West Central or South Alabama - You are 40 years of age or older Who may not be able to join: - You have a medical condition that causes severe memory or thinking problems, such as stroke, head injury, dementia, or Alzheimer's...

Who might be able to join this trial: - Adults aged 18 to 79 who have hearing loss in both ears, where the hearing loss developed after they had already learned to speak and understand language. - People who have worn properly fitted hearing aids in both ears for at least 30 days, with the fit verified using a standard...

Who might be able to join this trial: - You use a cochlear implant (a surgically implanted hearing device). Who may not be able to join: - People who are younger than 18 years old are not eligible to take part. Important: Always verify eligibility with the trial site directly before applying.

Who might be able to join this trial: - Adults aged 18 or older - People who can read and speak French well - People who are enrolled in the French Social Security system - People who have signed an informed consent form agreeing to take part - People who have normal vision or vision that is fully corrected (for exampl...

**Who might be able to join this trial:** **Group 1 – People with a cochlear implant:** - You have a cochlear implant made by Oticon Medical, in one ear only - You have been using your cochlear implant for at least 6 months - When tested in quiet conditions, you can correctly identify at least 40% of two-syllable word...

**Who might be able to join this trial:** - You are between 19 and 80 years old - You have been diagnosed with sudden hearing loss in one ear that has no known cause, confirmed through hearing and speech tests and a physical exam - You first noticed your hearing loss within the last 14 days and are being seen at the cl...

**Who might be able to join this trial:** - You are between 18 and 85 years old - You live in your own home or community (not in a care facility) - You plan to stay living in the local area for the full length of the study (3 years) - You speak and understand English fluently - You have a type of hearing loss that coul...

**Who might be able to join this trial:** - You are willing and able to follow all study procedures and can commit to the full length of the study - You are able to understand and sign a consent form agreeing to take part - You are 18 years of age or older - You have been diagnosed with squamous cell carcinoma of the...

Who might be able to join this trial: - You are 65 years of age or older - You are currently staying in a hospital geriatric ward or living in a care home (EHPAD) Who may not be able to join: - You have difficulty swallowing solid foods safely, such as cookies, which could cause food or liquid to go down the wrong way...

Who might be able to join this trial: - You speak English - You are visiting the emergency department for a low or medium urgency reason (not a life-threatening emergency) - You have scored 10 or higher on a hearing difficulty screening questionnaire, or answered "yes" to a single question about hearing problems - You...

Who might be able to join this trial: - People aged 18 or older. - People with some degree of hearing loss or difficulty processing sounds, ranging from mild to more severe. - People who are current or new patients at the Dartmouth Health Medical Center (DHMC) Otolaryngology clinic, or employees of Dartmouth College, D...

**Who might be able to join this trial:** - You are receiving cisplatin (a type of chemotherapy) as part of your cancer treatment - You are 18 years old or older - You are willing to sign a consent form agreeing to take part - You are reasonably well and able to carry out daily activities with little or no help (confir...

**Who might be able to join this trial:** - You are between 45 and 64 years old and have severe to profound hearing loss in both ears that developed after you learned to speak, and even with hearing aids you can only understand up to 70% of spoken words in a quiet setting (confirm with trial site) - Alternatively, you...

Who might be able to join this trial: - Children aged 7 or older who received a cochlear implant before the age of 2, people with some remaining hearing even with hearing aids, or people with normal hearing - Adults aged 18 or older who received a cochlear implant after they had already learned to speak and hear, or wh...

Who might be able to join this trial: - People diagnosed with sensorineural hearing loss (a type of hearing loss caused by damage to the inner ear or hearing nerve) - People who are scheduled to have cochlear implant surgery using a specific electrode called the CI422 Who may not be able to join: - People who have an...

**Who might be able to join this trial:** - You are between 18 and 80 years old - A brain scan (using a special type of MRI) has shown that your brain has low levels of a natural antioxidant called glutathione - You carry, or are suspected to carry, a specific genetic change in your mitochondrial DNA called m.3243A>G (...

**Who might be able to join this trial:** *For all participants:* - People who are over 18 years old - People who are covered by a social security system - People who have a good understanding of French, both spoken and written *For the group with age-related hearing loss (anticipated presbycusis):* - People over 40...

**Who might be able to join this trial:** - Adults aged 18 or older (Group A), or children aged 5 to 17 years and 11 months (Group B) - The ear to be implanted has severe hearing loss in a specific range, with a pure-tone average above 80 dB HL at key frequencies, and very poor word recognition even with hearing aids...

**Who might be able to join this trial:** - People aged 55 years or older - People who wear hearing aids in both ears - People who are able to give consent and communicate in English - People who have a phone that can run a mobile app required for the study - People who show signs of fall risk, such as feeling unstead...

**Who might be able to join this trial:** - You must be between 4 and 21 years old at the time of joining the trial - You must have been newly diagnosed with a brain tumor called medulloblastoma, confirmed by specialist review - Your tumor must not have spread to other parts of the brain or spine (called "M0 disease")...

Who might be able to join this trial: - Children aged 16 years or younger (for group 1) or 10 years or younger (for group 2) at the time consent is signed - Children diagnosed with hearing loss in both ears that is caused by the inner ear or hearing nerve (not by sound-blocking problems), ranging from mild to profound,...

Who might be able to join this trial: - Children whose nonverbal problem-solving or intelligence scores fall within a typical range (between 77 and 123 on a standard scale) - Children with normal hearing must have hearing thresholds at or below 20 dB HL across a range of sound frequencies - Children with hearing loss m...

Who might be able to join this trial: - People who are between 12 and 20 years old at the time of joining the trial - People who have been diagnosed with Osteogenesis Imperfecta (a condition affecting bone strength), of any type - People who are currently being seen and followed by a doctor at the CRMR OI (a specialist...

Who might be able to join this trial: - People who have had constant, ongoing tinnitus (ringing or noise in the ears) for at least 6 months - People whose tinnitus is bothersome, based on a standard questionnaire score and how loud they report it to be - People who are able to change or affect their tinnitus by moving...

**Who might be able to join this trial:** - Adults aged 18 or older - People who developed severe to profound hearing loss (in the ear or ears being implanted) after they had already learned to speak and hear - People who have had a CT scan of their cochlear implant electrode taken after surgery - People who had heari...

**Who might be able to join this trial:** - You received a cochlear implant at the Auditory Implant Center at China PLA General Hospital. - You are between 16 and 90 years old. - You have hearing loss and either had ringing in the ears (tinnitus) for more than 3 months before your cochlear implant surgery, or had no ti...

**Who might be able to join this trial:** *For the acoustic trauma military group:* - People aged between 18 and 65 years old - People who are active or reserve military personnel - People who have been diagnosed with noise-related hearing damage for at least one month - People who are regularly seen at the ENT depart...

**Who might be able to join this trial:** - You are 20 years old or older - You visited the Department of Otolaryngology (Ear, Nose and Throat) at Wonju Severance Christian Hospital and were diagnosed with sudden hearing loss, confirmed by a hearing test showing a significant drop in hearing (30dBHL or more across thre...

Here is the eligibility information in plain English: **Who might be able to join this trial:** - Children who were born deaf or became deaf before learning to speak, and who use a cochlear implant - Adults who could hear and speak before losing their hearing, and who now use a cochlear implant - Children who have nor...

**Who might be able to join this trial:** - Children who are enrolled in school in one of the 14 participating counties - Children who are at the point of first entry into elementary school - Children of any age, gender, race, or ethnicity may be considered **Who may not be able to join:** - No specific exclusion crit...

Who might be able to join this trial: - Both the child and their parent must speak Finnish Who may not be able to join: - The child has an existing hearing loss caused by damage to the inner ear or hearing nerve (known as sensorineural hearing loss) - The child has a developmental disorder - The child has previously h...

**Who might be able to join this trial:** - You are 18 years old or older and have moderate-to-severe or complete hearing loss in both ears, or are completely deaf in one ear - You have been approved by the Cochlear Implant Program at London Health Sciences Centre (LHSC) to receive a cochlear implant in one ear - Engli...

**Who might be able to join this trial:** - People who were diagnosed with a childhood cancer before the age of 18 - People whose cancer treatment included chemotherapy and/or radiation therapy - People who finished all cancer treatment at least 6 months ago, but less than 2 years ago - People currently being followed...

Who might be able to join this trial: - Children enrolled in one of the participating schools across the 3 study regions - Students in grades Kindergarten through 12th grade (K-12) who are part of the regular screening program at their school - Children of any age, gender, race, or ethnicity may be considered Who may...

Who might be able to join this trial: - People who are 18 years of age or older - People who have a non-cancerous ear tumour called a vestibular schwannoma (VS) on one side only, and whose medical team has already recommended either a type of focused radiation treatment (called stereotactic radiosurgery, or SRS) or a "...

**Who might be able to join this trial:** - Children or adults who have already received, or are planned to receive, a hearing implant in one or both ears from the company MED-EL (either at the same time or in separate procedures). - Children or adults who have already received, or are planned to receive, a non-surgic...

**Who might be able to join this trial:** *For people receiving a cochlear implant:* - You are 18 years old or older - You have been recommended for cochlear implant surgery based on French health authority guidelines, meaning you have severe to profound hearing loss and score 50% or below on a standard speech underst...

**Who might be able to join this trial:** - People aged 2 years or older (if the study involves any procedures or treatment) - People who are at risk of, suspected of having, have a history of, or currently have a diagnosed condition affecting hearing, balance, taste, smell, voice, speech, language, or another ear, no...

**Who might be able to join this trial:** - You have a pulsating/whooshing sound in your ear (called pulsatile tinnitus) that significantly affects your daily life - A scan has confirmed that your tinnitus is caused by an abnormal connection between arteries and veins near your brain, called a dural arteriovenous fist...

**Who might be able to join this trial:** - You are between 60 and 85 years old - You have been diagnosed with age-related hearing loss (sometimes called presbycusis) - Your hearing loss falls within a specific moderate range, measured by a hearing test (not too mild and not too severe — confirm exact hearing test resu...

**Who might be able to join this trial:** **For children receiving the cochlear implant (study subjects):** - A parent or guardian has signed and dated the permission form - The child has severe-to-profound hearing loss in one ear only, present from birth or developed before age 2, with normal or near-normal hearing i...

"Who might be able to join this trial: - People who are 18 years of age or older - People who can speak, understand, and read English - People who are a patient at one of the primary care clinics taking part in this trial Who may not be able to join: - People who are under 18 years of age Important: Always verify eli...

**Who might be able to join this trial:** - A parent or legal guardian (for child participants) and/or the adult participant must be willing to sign a consent form and agree to follow the trial's procedures. - A parent or legal guardian (for child participants) and/or the adult participant must be willing to consent t...

Who might be able to join this trial: - You must be at least 12 years old. - You must already have a cochlear implant and have had it for at least 6 months (any brand is acceptable). - Your hearing loss must have happened after you had already learned to speak and understand language (known as post-lingual deafness). -...

**Who might be able to join this trial:** - You have cochlear implants in both ears (either fitted at the same time or one after the other), and you wear both processors for at least 6 hours a day, every day, over the course of a month. - You were born with severe or profound hearing loss in both ears and received you...

Who might be able to join this trial: - You are an adult or child (aged 2 or older) who has a hearing impairment and uses either a cochlear implant or an auditory brainstem implant (ABI). - You do not have any other diagnosed communication or thinking/memory disorders beyond your hearing impairment. - You are able to t...

Who might be able to join this trial: - People of any age may be considered, depending on which group (cohort) within the trial they are being assessed for - People who have at least two changes (mutations) in a specific gene called the otoferlin gene - People who have been assessed and found to have severe hearing los...

**Who might be able to join this trial:** - You have been diagnosed with Ménière's disease in one ear only, confirmed using specific international medical guidelines (this includes having at least two episodes of vertigo lasting between 20 minutes and 12 hours, a particular type of hearing loss in one ear confirmed by...

**Who might be able to join this trial:** **For adults (with a cochlear implant):** - You are at least 18 years old - American English is your first language - You wear a cochlear implant made by Advanced Bionics (Clarion Hi-Focus I or a newer model), Cochlear, or MED-EL **For children (with a cochlear implant):** -...

Who might be able to join this trial: - Adults aged 18 or older who speak French - People who meet the medical criteria for receiving a cochlear implant - People who have had total hearing loss for less than 5 years Who may not be able to join: - People with certain nerve-related hearing conditions, such as auditory n...

**Who might be able to join this trial:** - Children who were born with profound deafness - Children who received their cochlear implant between 8 months and 18 months of age - Children who have had a cochlear implant (in one or both ears) for at least 3 months - Children who are between 11 months and 21 months old on...

**Who might be able to join this trial:** - Children between the ages of 5 and 17, or adults aged 18 and older, who either have normal hearing or have at least one cochlear implant (a device surgically placed to help with hearing) - Participants with a cochlear implant must also have some remaining low-frequency (low-...

Who might be able to join this trial: - You have been diagnosed through genetic testing with hearing loss caused by changes in both copies of a specific gene called otoferlin (OTOF), and you have had a hearing test to assess your hearing. Who may not be able to join: - You have genetic test results showing your hearin...

Who might be able to join this trial: - Adults aged 18 years or older who speak French - People who meet the medical criteria for receiving a cochlear implant Who may not be able to join: - People who have certain conditions affecting the hearing nerve or nearby structures, such as auditory neuropathy (a disorder wher...

**Who might be able to join this trial:** **Arm 1:** - Children who have a type of permanent hearing loss (called sensorineural hearing loss) in both ears and who meet the medical standards for receiving cochlear implants, and who are 5 years old or younger when the cochlear implant evaluation starts - Children whose...

**Who might be able to join this trial:** - People aged 18 or older - People whose first language (mother tongue) is French - People with little to no measurable hearing loss — specifically, an average hearing loss of less than 30 dB in each ear when tested individually with headphones (confirm with trial site for exa...

Who might be able to join this trial: - The child must be between 7 and 17 years old - The child must have normal vision, with glasses or contact lenses if needed - The child must be able to understand the instructions given during the study - The child's parent or guardian must have been informed about the study and s...

Who might be able to join this trial: - You are between 8 and 17 years old and have had a cochlear implant for at least 1 year - You are currently being seen and followed at Hôpital Necker-Enfants Malades - You mainly communicate by speaking French out loud - Your hearing test results with the cochlear implant show a c...

**Who might be able to join this trial:** - People aged between 60 and 90 years old - People who are right-handed - People whose first language is English - People who score 25 points or above on a standard memory and thinking test called the Montreal Cognitive Assessment (MoCA) - For people with hearing loss, a hearin...

Who might be able to join this trial: - Children who are between 2 and 6 years old - Children who are currently attending a community-based preschool program Who may not be able to join: - Children who have already been diagnosed with permanent hearing loss, based on what a parent or school has reported - Children who...

**Who might be able to join this trial:** - People with mild to moderate memory or thinking difficulties, with a score of 15 or higher out of 30 on a standard cognitive test (called the MMSE) - People who speak and understand French - People who have given written agreement to take part in the trial - People who are co...

Who might be able to join this trial: - People who are over 60 years of age - People who have been diagnosed with mild dementia or mild cognitive impairment at a participating memory evaluation centre - People who have mild to moderate hearing loss in both ears and are not currently using hearing aids - People who have...

**Who might be able to join this trial:** - People between 55 and 75 years old - People with mild to moderate hearing loss that developed in adulthood, based on a standard hearing test result in their better ear - People whose hearing loss is at a level where hearing aids could help, shown by being able to correctly r...

**Who might be able to join this trial:** - Your baby was born in New York State between September 27, 2023 and October 1, 2024 - Your baby received an evaluation for congenital CMV (a virus that can be passed from mother to baby before birth) at an officially designated New York State referral clinic - Your family is...

Who might be able to join this trial: - The child must be between 3 and 10 years old - The child must have hearing loss in one or both ears, where the inner ear is not working properly, measured above a certain level across several sound frequencies - The child's parents or guardians must have signed a consent form agr...

**Who might be able to join this trial:** - People with congenital (present from birth) hearing loss where hearing thresholds are 65 dB or worse, who have already received gene therapy with follow-up care, are planning to receive gene therapy, or have received a cochlear implant. - Healthy participants with normal hea...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have been recommended for a cochlear implant (in one or both ears, either at the same time or one after the other) due to severe to profound hearing loss in both ears, where understanding speech remains very difficult even with hearing aid...

**Who might be able to join this trial:** **Part A:** - Healthy volunteers (people without significant health conditions) **Part B:** - People who have sudden hearing loss in one ear only (of unknown cause), where the hearing loss measures greater than 45dB on a hearing test, and the other ear has near-normal hearing...

**Who might be able to join this trial:** - You are 18 years old or older - You meet the standard requirements for getting a cochlear implant in your country - You have severe to profound hearing loss in the ear to be implanted, based on specific hearing test results - Your hearing at low pitches (500 Hz) is not too fa...

Who might be able to join this trial: - People who are able to give their own consent to participate, or for children, a parent or guardian who is able to consent on their behalf. - People who are willing and able to sign a written consent form (or have a legally authorised representative do so on their behalf). - Peop...

**Who might be able to join this trial:** - People who are military Veterans, male or female, of any racial or ethnic background - People who are between 18 and 60 years old - People who have been close enough to a high-intensity blast (such as from an RPG, IED, or mortar) to feel the heat or pressure from it - People...

**Who might be able to join this trial:** - People aged 18 or older - People with normal hearing - People who have at least one specific small bone (the incus or the tip of the malleus, called the umbo) visible when a doctor looks inside the ear with a small light and camera tool - People whose eardrum pressure test (a...

**Who might be able to join this trial:** - You are 18 years of age or older at the time of signing up for the trial - You developed hearing loss after you had already learned to speak, and you have moderate to severe or profound hearing loss in both ears that affects certain sound frequencies in a specific pattern (co...

Who might be able to join this trial: - You are between 30 and 55 years old (male or female) - You first noticed hearing loss in both ears after the age of 16 - You have had genetic testing that shows changes (mutations) in a gene called GJB2 Who may not be able to join: - Your hearing loss has a known cause that is n...

Who might be able to join this trial: - People who have tinnitus in both ears that has been diagnosed as long-term subjective tinnitus (the type where only the person affected can hear the sound). - People who are male or female, aged between 18 and 60 years. - People who are right-handed, able to follow the study requ...

Who might be able to join this trial: - Adults aged 18 years or older who have been diagnosed with severe to profound hearing loss and are already planning to have cochlear implant surgery at the University of Miami. - People with profound sensorineural (nerve-related) hearing loss may be eligible for the safety portio...

**Who might be able to join this trial:** - You are between 18–35 years old with normal hearing, OR between 60–80 years old with normal hearing, OR between 60–80 years old with a moderate hearing loss in both ears. - If you have normal hearing, your hearing test results must fall within a specific healthy range at var...

**Who might be able to join this trial:** - Be between 6 and 16 years old at the time of joining the trial - Speak French as their main way of communicating - Be able to complete a specific French hearing test called the Simplified French Matrix test in Noise - (One group) Use or be eligible to upgrade to a Sky cochlea...

Who might be able to join this trial: **For people with chronic tinnitus:** - People who have had tinnitus for 6 months or longer - People aged 20 to 55 years old, any gender, and right-handed - People whose ear canals are clear and whose eardrums are intact - People whose average hearing level in both ears is within...

**Who might be able to join this trial:** - You are 18 years old or older, of any gender - You have been diagnosed with a mitochondrial disease that affects multiple parts of the body - You have a specific confirmed genetic change in your mitochondrial DNA called the m.3243A>G mutation, with test results showing it is...

**Who might be able to join this trial:** - You are 18 years of age or older - You have hearing loss that developed after you learned to speak, and it has been confirmed by a doctor as a specific type called sensorineural hearing loss - You have been assessed as a suitable candidate for a cochlear implant based on your...

Who might be able to join this trial: - People who are able to understand and recognise spoken words in English - People who speak North American English fluently - Adults between the ages of 18 and 65 years old - People whose hearing test results fall within one of these ranges: mild hearing loss (up to 25 decibels of...

**Who might be able to join this trial:** - People aged 18 or older - People who are registered with the French social security system - People who have provided signed consent to participate - People who had no age-related hearing loss before starting cancer treatment (applies to groups A and C) - People with no know...

**Who might be able to join this trial:** - You are male or female and aged 18 or over - You are scheduled to have surgery in a specific area at the base of the brain called the cerebellopontine angle (this includes procedures such as microvascular decompression, vestibular neurotomy, or removal of a meningioma or sch...

Who might be able to join this trial: - Children and teenagers between the ages of 10 and 18 years old - Children of any gender or ethnic background - Children who have been assessed and found to have "severe" symptoms of both tinnitus (ringing or noise in the ears) and misophonia (strong negative reactions to certain...

**Who might be able to join this trial:** - Adults aged 18 to 80 years, of any gender - People with a normal-looking ear canal and eardrum on examination by a doctor - People who are already scheduled for a specific type of brain surgery involving an area near the ear called the cerebellopontine angle (a procedure cal...

Who might be able to join this trial: - Adults who have developed hearing loss as an adult (not from birth or childhood) - People with mild-to-moderate hearing loss that affects both ears - People who feel or notice that they have hearing loss in both ears - People who have never worn hearing aids before Who may not b...

Who might be able to join this trial: - People who are between 18 and 60 years old Who may not be able to join: - People who have medical reasons that prevent them from having an MRI or CBCT scan (a type of detailed X-ray) - People who have serious medical conditions - People who have any neurological or psychiatric c...

**Who might be able to join this trial:** - You are between 18 and 75 years old - You had normal hearing and normal speech and language development as a young child - If you are a younger participant with typical hearing: your hearing test results show good hearing across a range of sound frequencies (no significant he...

**Who might be able to join this trial:** - You have a non-cancerous inner ear tumour (called a vestibular schwannoma) on one side only, and it has been growing over time. - Your tumour is larger than 2 mm in size. - You have severe hearing loss in the ear affected by the tumour, confirmed by a hearing test. - You are...

**Who might be able to join this trial:** - People who have a confirmed diagnosis of testicular cancer and whose doctors have recommended a chemotherapy treatment that includes the drug cisplatin, based on current medical guidelines. - Men between the ages of 18 and 45 years old. - People whose planned cisplatin treat...

Who might be able to join this trial: - You are an adult living in Saudi Arabia - You are between 18 and 65 years old - Both men and women can participate - You have been diagnosed with profound hearing loss or deafness - You are able to communicate using Saudi Sign Language Who may not be able to join: - You are unde...

**Who might be able to join this trial:** - You are willing and able to sign a written consent form agreeing to take part - You are a native Finnish speaker - Your hearing is normal for your age - (For people receiving treatment): You have been diagnosed with a cancer that will be treated with the goal of curing it, us...

Who might be able to join this trial: - You are between 18 and 85 years old - You have mild to moderate hearing loss in both ears that started in adulthood and stays roughly the same (does not fluctuate), with both ears being at a similar level of hearing loss - You have never used hearing aids before - English is your...

**Who might be able to join this trial:** - You have been diagnosed with Usher Syndrome Type 1B through genetic testing, specifically caused by a change (mutation) in a gene called MYO7A - You are willing and able to follow all the requirements of the study, as explained in the consent process **Who may not be able to...

Who might be able to join this trial: - Adults who have been diagnosed with moderate-to-profound hearing loss in both ears and are scheduled to receive a cochlear implant in one or both ears at the Mayo Clinic in Rochester, MN. Who may not be able to join: - People who are having a cochlear implant replaced or updated...

Who might be able to join this trial: - Adults aged 18 or older who are being seen by NHS ear, nose, throat (ENT) or hearing services for tinnitus (ringing or noise in the ears) that is not caused by a heartbeat sound and is not linked to another underlying condition. - People who have been experiencing tinnitus for at...

Who might be able to join this trial: - People who are 18 years of age or older - People who have tinnitus (ringing or noise in the ears) that has no known medical cause and is only heard by the person themselves - People who have a sufficient understanding of English to be able to give informed consent to participate...

**Who might be able to join this trial:** - Adults between 18 and 80 years old - People who have had ongoing tinnitus (ringing or noise in the ears that only they can hear) for at least 3 months - People who score 38 or higher on a standard tinnitus questionnaire called the Tinnitus Handicap Inventory (THI), which mea...

**Who might be able to join this trial:** - People aged 18 years or older. - People with normal hearing or up to moderately severe hearing loss (based on specific hearing test results in both ears). - People experiencing tinnitus (ringing or noise in the ears) in one ear only, or worse in one ear than the other, where...

Who might be able to join this trial: - Adults aged 18 or older who are able to give their informed consent to participate - People who have been diagnosed with a type of head and neck cancer (called HNSCC) affecting areas such as the mouth, throat, voice box, nasal sinuses, skin, or nearby lymph nodes in the neck — in...

Who might be able to join this trial: - People aged 18 or older - People who regularly use a cochlear implant that has at least 18 active electrodes and who keep up with their programming appointments - People who received their cochlear implant at least 6 months ago and who also wear a hearing aid in the opposite ear...

**Who might be able to join this trial:** - People who have a type of hearing loss caused by damage to the inner ear or hearing nerve (called sensorineural hearing loss) and have already received, or are planned to receive, a cochlear implant in one or both ears using one of these specific FDA-approved devices: Advanc...

**Who might be able to join this trial:** - You are a candidate for a cochlear implant in one or both ears, based on current US FDA guidelines - You have enough remaining hearing in the ear to be implanted to support a specific type of hearing measurement test, as decided by the study doctor - You will be receiving a s...

**Who might be able to join this trial:** - Children who are between 8 and 10 years old - Children who have a consistent (ongoing) level of hearing impairment - Children who are able to understand and follow instructions **Who may not be able to join:** - Children who have any current or long-term illness or medical c...

Who might be able to join this trial: - People who have a confirmed genetic diagnosis showing changes in both copies of the CABP2 gene, along with a hearing test on record Who may not be able to join: - People whose genetic testing points to a hearing condition caused by a gene other than CABP2 Important: Always veri...

**Who might be able to join this trial:** - You developed hearing loss as an adult, in both ears, and it is mild to moderate in severity (confirmed by a hearing test) - You are 40 years of age or older - You have not worn hearing aids for more than 3 months in total previously - You are able to read and understand pati...

Who might be able to join this trial: - People who have class one obesity (the first level of obesity as measured by body weight guidelines) - People who have metabolic syndrome (a combination of conditions such as high blood pressure, high blood sugar, and excess body fat around the waist) - People who have chronic su...

Who might be able to join this trial: - You are considered obese (carry excess body weight) - Your Body Mass Index (BMI) is between 30 and 40 (a measure of body weight relative to height) - You are male and have tinnitus (ringing or noise in both ears) that you have experienced for at least 24 weeks - You are male and...

**Who might be able to join this trial:** - You (or your child's legal guardian) must be willing to give written consent to take part and attend all scheduled follow-up visits. - You or your child must be able to communicate and follow instructions from the study team, with the help of a guardian if needed. - You or y...

"Who might be able to join this trial: - Adults aged 18 or older who speak French - People who meet the medical criteria for receiving a cochlear implant (a surgically placed hearing device) Who may not be able to join: - People with certain nerve-related hearing conditions, specifically auditory neuropathy (where sou...

**Who might be able to join this trial:** - You are 18 years old or older - You have pulsatile tinnitus (a rhythmic, heartbeat-like ringing or whooshing in your ear) that has lasted more than three months and significantly affects your daily life - When a doctor presses on the jugular vein on the same side as your affe...

**Who might be able to join this trial:** - You are between 18 and 55 years old at the time of signing the consent form - You are fluent in English **Who may not be able to join:** - Your ear pressure test (called a tympanometry) showed unusual or abnormal results - Your hearing test showed problems detecting sounds b...

Who might be able to join this trial: - You are 18 years old or older and speak French - You have already been assessed and meet the medical requirements to receive a cochlear implant Who may not be able to join: - You have a condition affecting the hearing nerve rather than the inner ear, such as auditory neuropathy...

Who might be able to join this trial: - People who have a confirmed diagnosis of H syndrome, proven through genetic testing Who may not be able to join: - No specific exclusion criteria have been listed for this trial (confirm with trial site) Important: Always verify eligibility with the trial site directly before a...

Who might be able to join this trial: - You have hearing loss and do not currently use hearing aids - You have hearing loss and currently use hearing aids - You have a cochlear implant on one side only, and use a hearing aid in the other ear Who may not be able to join: - No exclusion criteria were listed in the offic...

**Who might be able to join this trial:** - You are Chinese, right-handed, and between 60 and 80 years old - You have had tinnitus (ringing or noise in the ears) for at least 3 months - You have sleep problems, shown by scoring above 5 on a standard sleep quality questionnaire called the PSQI - You are able to manage y...

Who might be able to join this trial: - People who are 60 years of age or older - People who speak English or Spanish - Group 1: Older adults whose hearing is considered normal (hearing test results below a certain threshold in both ears) - Group 2: Older adults who have hearing loss in both ears and are not currently...

Who might be able to join this trial: - Adults aged 18 or older who experience subjective tinnitus (a ringing, buzzing, or similar sound heard in the ears or head that only the person themselves can hear) - People who have had tinnitus for 3 months or longer, where the tinnitus feels burdensome, and where this has eith...

**Who might be able to join this trial:** - You have been diagnosed with a genetic condition that affects the light-sensing cells at the back of your eye (called photoreceptors). - Your vision in the eye being studied falls within a specific range of vision loss — the exact range depends on which phase of the trial yo...

Who might be able to join this trial: - You are considered obese (carry excess body weight) - You have tinnitus (ringing or noise in the ears) in both ears that has been present for a long time - You have been diagnosed with mild obstructive sleep apnea (a mild form of interrupted breathing during sleep) - The trial is...

**Who might be able to join this trial:** - You are 18 years old or older and have had balance problems affecting both ears for more than 1 year, with little or no improvement from standard balance rehabilitation treatment - Your doctor believes your symptoms are unlikely to improve further with conventional treatment...

Who might be able to join this trial: - You are willing and able to sign a consent form agreeing to take part in the study - You mainly live in Innsbruck or the Innsbruck-Land region of Austria Who may not be able to join: - People who are held or restricted by a court order, any other legal process, or are placed in...

Who might be able to join this trial: **Otosclerosis Group:** - Adults who have been diagnosed with a condition called otosclerosis, confirmed through hearing tests and clinical assessment - People who have high-resolution CT scan images of the ear area and hearing test results available - People who have had a specif...

Who might be able to join this trial: - Adults between 18 and 60 years old - People who speak and understand English fluently - People who have mild-to-moderate hearing loss, confirmed by a standard hearing test (where the average hearing level falls between 25 and 55 dB across a range of sound frequencies) - People wh...

Who might be able to join this trial: - A parent or legal guardian, as well as the child, must have signed a consent form agreeing to take part. - The child must be between 12 and 17 years old (inclusive). - The child must have a specific type of hearing loss that matches the device's approved use — either a conductive...

Who might be able to join this trial: - Children who are currently in grades five through eight - Children who are deaf or hard of hearing - Children who use both spoken English and American Sign Language (ASL) - Children who have hearing loss in both ears - Children who are able to read and understand certain sentence...

**Who might be able to join this trial:** **For people with a cochlear implant (up to 120 participants):** - Adults aged 18 to 99 years old - People whose cochlear implant has been switched on and in use for more than one year - People who meet the research eligibility requirements of the Iowa Cochlear Implant Project...

**Who might be able to join this trial:** - Pharmacy technicians who hold a valid licence to practise in the state of Alabama or Mississippi - Pharmacy technicians who currently work in rural communities in Alabama or Mississippi - Adults aged 18 or older who have mild to moderate hearing loss and who live in a rural c...

Who might be able to join this trial: - You have agreed to take part in the study and given your consent - You are aged 18 or older but under 85 years old - You have been experiencing tinnitus (ringing or noise in the ears that only you can hear) for more than 3 months - Your tinnitus score on a standard questionnaire...

**Who might be able to join this trial:** - People aged between 60 and 85 years old - People diagnosed with age-related hearing loss, meaning hearing loss that affects both ears equally, develops gradually, and mainly affects the ability to hear high-pitched sounds and understand speech - People whose age-related hear...

Who might be able to join this trial: - People who have a metal-on-metal (MoM) hip implant, from any of the participating clinics - People who have had their metal-on-metal hip implant revised (replaced or updated through surgery) - People who are willing to take part in the study - People who can speak and write in Du...

**Who might be able to join this trial:** - People who are able to give their informed consent to participate - People who are able to describe what they hear and give feedback on their listening experience - People who are 18 years of age or older - People who have a HiResolution Bionic Ear System cochlear implant (o...

Who might be able to join this trial: - People who are experiencing tinnitus that is causing them distress - People who have a sufficient level of English and hearing ability to participate in the study - People who have already completed all relevant medical and hearing-related tests and any treatment for an underlyin...

**Who might be able to join this trial:** - You are 18 years old or older - You have been newly diagnosed with a condition called Idiopathic Intracranial Hypertension (IIH) — meaning raised pressure in the skull with no clear cause — within the last 3 months - A brain scan (MRI) has shown a narrowing in specific veins...

**Who might be able to join this trial:** - The child is between 4 and 6 years old at the time of joining the trial - The child mainly communicates using spoken French - The child has been diagnosed with hearing loss in one ear only, or significantly worse hearing in one ear than the other — either with no hearing loss...

Who might be able to join this trial: - You are between 60 and 100 years old - You speak English - You have been diagnosed with Alzheimer's disease or a related form of dementia, based on standard medical guidelines - You have hearing loss in your better ear that is above a mild level (confirmed by a hearing test) - Yo...

Who might be able to join this trial: - Adults aged 18 or older who have had a Ponto implant procedure performed outside of a traditional operating room setting, from 2019 onwards - People who have signed a consent form agreeing to participate (this applies to those who will be asked to fill out questionnaires) Who ma...

**Who might be able to join this trial:** - You must have already completed all required activities in a previous related study called the CLTD5759 CI-DEX study, and the location where you took part must be selected for this new trial. - You must have received a specific type of cochlear implant (either a CI632D or CI6...

**Who might be able to join this trial:** - Be between 4 years and 9 years 11 months old - Have a permanent hearing loss that was present before learning to speak, caused by a problem in the inner ear or hearing nerve - Use spoken English as their main language at home (more than half of the time) - Score at least 70 o...

Who might be able to join this trial: **For children:** - The child has been diagnosed with cerebral palsy - The child is between 6 and 12 years old - The child's family has given approval for them to take part in the study **For families:** - You have a child between 6 and 12 years old who has been diagnosed with ce...

**Who might be able to join this trial:** - You are 18 years old or older - You have a confirmed diagnosis of Idiopathic Intracranial Hypertension (IIH) — a condition where pressure in the skull is too high — that was made using a specific set of medical criteria, and you have been on standard medical treatment includi...

Who might be able to join this trial: - People who have been diagnosed with mild cognitive impairment (early-stage memory and thinking difficulties) based on a specific set of medical guidelines known as Petersen's criteria - People who have at least some hearing difficulty in one or both ears, as shown by a specific h...

**Who might be able to join this trial:** - You became deaf or lost significant hearing after you had already learned to speak and understand language (not deaf from birth or early childhood) - You are 18 years of age or older - You are a new cochlear implant recipient using a device made by Cochlear Americas, and you...

**Who might be able to join this trial:** - People aged 18 years or older - People who have sudden hearing loss in one ear only, where the hearing loss developed within 72 hours and has been present for 14 days or less - People whose hearing in the affected ear, measured across specific sound frequencies, shows a signi...

**Who might be able to join this trial:** - A parent or legal guardian (and the child, where appropriate for their age) must be willing to sign a consent form agreeing to take part - Children aged 3 to 11 years old - Children who have a type of hearing loss called conductive or mixed hearing loss, where the inner ear'...

Who might be able to join this trial: - You are 18 years old or older - You have been confirmed to have mild to severe hearing loss in both ears (based on tests done at the start of the study) - You are able and willing to attend follow-up appointments at 6 weeks and 12 weeks after joining Who may not be able to join:...

Who might be able to join this trial: - People who are scheduled to receive a cochlear implant (a hearing device surgically placed in the ear) made by Cochlear Americas - People who are willing to take part in the study Who may not be able to join: - People who have had previous ear surgery, were born with an ear abno...

**Who might be able to join this trial:** - Adults aged 18 to 55 at the time of signing the consent form whose main concern is tinnitus (ringing or noise in the ears) - People who have been experiencing tinnitus for at least 30 days - People whose tinnitus scores at least 12 on a standard tinnitus severity questionnai...

**Who might be able to join this trial:** - (For the hearing loss group) You were born with hearing loss, your hearing loss is significant (65 dB or greater), and you have already received hearing aids, a cochlear implant, or gene therapy for your hearing - (For the hearing loss group) You are between 1 and 35 years o...

**Who might be able to join this trial:** - You are 18 years old or older - You are covered by a social security/health insurance system - You have moderate to severe hearing loss in both ears that developed after you learned to speak, and you have been wearing hearing aids for more than 6 months - You wear your hearin...

Who might be able to join this trial: - People who are 18 years of age or older - People who have no known structural or physical abnormalities in either ear - People who speak English - People who are planning to receive a cochlear implant in one ear, or who have already had one placed but it has not yet been switched...

Who might be able to join this trial: - Adults between 18 and 80 years old (male or female) - People who are able to give their informed consent to take part in the study - People who have severe or very serious pulsatile tinnitus (a rhythmic ringing or whooshing sound in the ears) that temporarily improves when pressu...

**Who might be able to join this trial:** - You are 18 years of age or older at the time of signing the consent form - You speak English or Spanish fluently - You have had ringing or buzzing in your ears (tinnitus) for more than 30 days, and you notice it during at least 75% of your waking hours - Your tinnitus is at l...

**Who might be able to join this trial:** - You are an adult man or woman who is currently serving in the military or is a veteran, and you are seeking treatment for PTSD - You have been diagnosed with PTSD - You have had at least one mild traumatic brain injury (also called a concussion) at some point - You are able t...

Who might be able to join this trial: - You are between 18 and 95 years old - You have a significant level of hearing loss (classified as N3 or N4, which means moderate to severe — confirm with trial site if unsure of your level) - You have previous experience using hearing aids - You can speak and understand English f...

Who might be able to join this trial: - Adults aged 18 or older - People who have had a Cochlear Baha BI300 implant fitted together with a Cochlear Baha BA300 Abutment (known as the Baha Connect System) - People who have a type of hearing loss — either mixed or conductive — in the ear where the Baha Connect System is f...

**Who might be able to join this trial:** **For patients (both parts of the study):** - You are 18 years old or older (there is no maximum age limit) - You have recently been given your first NHS hearing aid(s) through the NHS, mainly because of hearing loss - You are willing and able to agree to take part after being...

**Who might be able to join this trial:** - You have severe hearing loss and have been identified as a suitable candidate for a cochlear implant - You are 18 years of age or older - Your middle ear is working normally, with no current middle ear infections - You are able to speak and understand Dutch - You have chosen...

Who might be able to join this trial: - Children within specific age ranges: 2 to 4.5 years, 4.5 to 5.5 years, or 5.5 to 7 years old - For the control groups: children whose hearing has been confirmed as normal through standard hearing tests (pure tone audiometry and tympanometry) - For the hearing-impairment groups: c...

Who might be able to join this trial: - People who are between 25 and 55 years old - People who can read and speak English well - People in the traumatic brain injury group must have a history of traumatic brain injury caused by a blast or physical trauma - People in the normal hearing comparison group must have no his...

Who might be able to join this trial: - People who are willing and able to take part in therapy conducted online. - People who are proficient in the Polish language. - People who are 18 years of age or older. - People who have been experiencing chronic tinnitus (a persistent ringing or noise in the ears) for at least 3...

Who might be able to join this trial: - People who have had tinnitus (ringing or noise in the ears) for more than six months, with or without hearing loss - People whose tinnitus has no physical structural cause found in the ear or surrounding bone area - People who are either not currently receiving any treatment for...

Who might be able to join this trial: - Adults between the ages of 55 and 80 years old - People with normal hearing or hearing loss related to aging, whether or not they use hearing aids Who may not be able to join: - People who have a history of traumatic brain injury or hearing damage caused by loud noise - People w...

**Who might be able to join this trial:** - You are 18 years old or older - You have been experiencing both tinnitus (ringing in the ears related to touch or movement) and jaw joint problems (TMD) for more than 6 months - Your teeth are in good health, with enough teeth on both sides of your mouth at least up to the se...

**Who might be able to join this trial:** - People who have given written consent to participate (or whose legal representative has done so on their behalf) - People who are willing and able to attend hearing tests at the start of the trial and at regular intervals throughout - Adults aged 18 years or older - People w...

Who might be able to join this trial: - Males and females of any age (infants, children, teenagers, and adults) who have been diagnosed with a type of hearing loss called conductive or mixed hearing loss in one or both ears - Males and females of any age who attend Atrium Health-Audiology for a routine clinic visit and...

Who might be able to join this trial: - You are over 18 years old - You have hearing loss in both ears equally (the same level of loss on both sides), caused by damage to the inner ear or hearing nerve rather than a blockage or mechanical problem - You developed your hearing loss as an adult (not before or during child...

**Who might be able to join this trial:** This trial has three groups. The criteria differ slightly between groups, as outlined below. **All three groups require:** - Being between 20 and 60 years of age - Having hearing test results in the normal range across key frequencies (confirmed by a standard tone hearing tes...

Who might be able to join this trial: - People who are 18 years of age or older, of any gender. - People who have been diagnosed with sudden sensorineural hearing loss, meaning a hearing loss of more than 30 decibels across at least three connected sound frequencies that developed within 3 days. - People whose hearing...

Who might be able to join this trial: - Children who have moderate to severe hearing loss - Children who need a routine dental cleaning (also called a prophylaxis) - Children who are in generally good health Who may not be able to join: - Children who have severe cognitive impairment or developmental disorders - Child...

**Who might be able to join this trial:** - You have mild to moderate hearing loss (between 20dB and 50dB) in your better ear, based on standard hearing measurements - You need a fairly loud sound level to understand speech clearly, even in a quiet room (confirm with trial site) - You have noticeably more difficulty u...

Who might be able to join this trial: - People whose main health concern is tinnitus — meaning they hear sounds in their ears or inside their head when no external sound is present. - People with long-term tinnitus lasting more than 6 months, a tinnitus impact score of 38 or higher on a standard questionnaire (called t...

**Who might be able to join this trial:** - You have been officially diagnosed with Meniere's disease in one or both ears - You are between 18 and 60 years old - You have been experiencing fluctuating symptoms or ongoing balance problems for at least 3 months - You have sufficient mental clarity to take part in balance...

Who might be able to join this trial: - You must be at least 3 years old - You must have been diagnosed with Usher syndrome type 1 (a condition causing profound deafness from birth, balance problems, and progressive vision loss) in both eyes, confirmed by a specific genetic test showing changes in both copies of the MY...

**Who might be able to join this trial:** - You have been diagnosed with a head and neck cancer (confirmed by a lab test on a tissue or cell sample) and your treatment plan includes a chemotherapy drug called cisplatin, given either weekly (7 doses) or every 3 weeks (3 doses), adding up to a total dose of at least 200...

**Who might be able to join this trial:** - Adults aged 18 years or older - People who experience mild to moderate hearing difficulties, shown by answering "yes" to at least one of these: trouble hearing speech in noisy places, difficulty following conversations in groups, trouble hearing on the phone, feeling tired f...

Who might be able to join this trial: - You are 18 years of age or older at the time you give your consent to join. - The ear to be implanted has significant hearing loss, measured at a level of 70 dB or worse across key sound frequencies (this is a specific hearing test result — confirm with trial site). - Even with a...

Who might be able to join this trial: - You may be eligible if you have mild-to-moderate hearing loss caused by a problem in the inner ear (cochlea), meaning your hearing test shows at least a moderate degree of difficulty hearing certain sound frequencies, getting worse at higher pitches, and you would benefit from a...

**Who might be able to join this trial:** - The participant (and/or their legal guardian) must be willing to give written consent to take part, attend all follow-up visits, and understand what the trial involves and what results may or may not be possible - The participant must be able to communicate with the research...

Who might be able to join this trial: - You currently use a bone-anchored hearing system (BAHS) with a specific type of attachment (abutment) that is compatible with Oticon Medical devices - You have signed a form agreeing to take part in the study - You are 18 years of age or older - You have a specific type of hearin...

**Who might be able to join this trial:** - People who are between 45 and 65 years old at the time of their first screening visit. - People who are willing and able to give written consent and follow the study requirements. - People whose hearing test results show only mild or no hearing loss at standard sound frequen...

Who might be able to join this trial: - Babies who are between 0 and 1 month old at the time of their newborn hearing screening - Babies who had an inconclusive result on their second newborn hearing screening test (in one or both ears), with that inconclusive result occurring between August 2024 and the end of July 20...

**Who might be able to join this trial:** - Children aged 5 to 17, or adults aged 18 and older - You have at least one cochlear implant (a device surgically placed in the ear to help with hearing) and have hearing loss ranging from mild to profound in both ears, with some remaining natural hearing ability at low-pitch...

**Who might be able to join this trial:** - You are between 18 and 70 years old - You are planned to receive a high-dose cisplatin-based chemotherapy treatment, with a total planned dose above 200 mg/m² and each individual dose above 50 mg/m² (confirm with trial site if unsure about your dose) - You may also be receiv...

**Who might be able to join this trial:** - People who have severe or profound hearing loss (65 decibels or more) and are already scheduled to receive a cochlear implant. - People of any age or gender may be considered. - People whose first language is Mandarin Chinese. - People (or their legal guardian, if applicable)...

Who might be able to join this trial: - You are between 50 and 85 years old (any gender) - You have been diagnosed with age-related hearing loss, meaning your hearing has slowly gotten worse over time, mainly affecting your ability to hear higher-pitched sounds and understand speech - Your better ear has moderate to se...

**Who might be able to join this trial:** - Adults between 18 and 80 years of age - People who have had ongoing tinnitus (ringing or noise in the ears) that they can hear subjectively, lasting more than 3 months but no longer than 5 years - People whose tinnitus is mainly tonal in nature (a steady tone or ringing), in...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been actively using hearing aids for at least 3 months - People whose hearing loss levels (from mild to profound, in both ears) fall within the range that the trial devices are designed to fit - People who have the mental and physic...

Who might be able to join this trial: **Group 1:** - You have hearing loss in both ears, ranging from mild to complete (total) hearing loss **Group 2:** - Your hearing is within the normal range (confirmed by a standard hearing test result below 20dB) - Your cognitive (thinking), language, and reading/writing develop...

Who might be able to join this trial: - People who have hearing loss in one ear only, where the hearing loss is either conductive (sound not reaching the inner ear properly) or mixed (a combination of types), and the eardrum is intact - People whose hearing tests show an air-bone gap (a measure of how much sound is bei...

Who might be able to join this trial: - People who are between 21 and 80 years old - People who have subjective tinnitus (ringing or noise in the ears that only they can hear) and rate its impact at 1 out of 10 or higher on a tinnitus scale, whether that relates to the sound itself, distress, or quality of life Who ma...

Who might be able to join this trial: - Children who have severe to profound hearing loss that was present from birth or before they learned to speak - Children who received a cochlear implant between 8 and 24 months of age - Children who are at least 24 months (2 years) past their implant surgery - Children whose pare...

Who might be able to join this trial: - You have had bothersome ringing or noise in your ears every day for at least 3 months, with a symptom score showing it significantly affects your life (TFI score above 15 — confirm with trial site if unsure how this is measured) - Your hearing is within the normal range across a...

Who might be able to join this trial: - People who have had a sudden drop in hearing in one ear only, where the hearing loss started within the last 72 hours and affected at least two connected sound frequencies by 20 decibels or more. - People who are able to be enrolled in the trial within 14 days of when the hearing...

**Who might be able to join this trial:** - You are 18 years of age or older (there is no upper age limit) - You scored at a certain level or below on a specific hearing test called the DTT (a speech-in-noise test), taken without hearing aids if you normally wear them - You either do not use any hearing devices, or you...

**Who might be able to join this trial:** *For children with cochlear implants:* - Children and teenagers between 6 and 18 years old - People with normal vision, including those whose vision is corrected with glasses or contact lenses - People who were born deaf or lost their hearing before learning to speak, with sev...

Who might be able to join this trial: - Children who are in group 7 of a Dutch primary school (similar to Year 6 in the UK). - Children whose parent(s) or guardian(s) have given their written permission for them to take part. - Parents or guardians whose child is already taking part in the trial. Who may not be able t...

Who might be able to join this trial: - Adults aged 18 or older who have been clinically diagnosed with retinitis pigmentosa or a similar condition where the retina gradually deteriorates over time - People who are currently using a device called the OkuStim® System for transcorneal electrical stimulation (a treatment...

"Who might be able to join this trial: **Normal Hearing Group** - People who have given voluntary written consent before any screening takes place (or whose legal representative has done so) - People who are at least 18 years old at the time of signing the consent form - People whose hearing test results show sound is...

**Who might be able to join this trial:** - You are between 18 and 75 years old (any gender) - You have one or more symptoms linked to "Cerebral Tinnitus Syndrome" that have been present for at least 3 months - After a thorough medical check-up, doctors suspect that a narrowing of a vein in your neck (called the intern...

**Who might be able to join this trial:** - Adults between 18 and 65 years of age - People who have been diagnosed with sudden unexplained hearing loss — specifically, a significant drop in hearing across three connected sound frequencies — within 14 days of their symptoms starting - People whose hearing loss did not i...

**Who might be able to join this trial:** - People aged between 18 and 70 years - People who have been diagnosed with sudden sensorineural hearing loss (a type of unexplained hearing loss that came on within 72 hours and met specific hearing test thresholds) - People whose hearing loss affects one ear only, and who had...

Who might be able to join this trial: - Children who are between 8 and 12 years old - Children who have hearing loss in both ears - Children whose hearing loss is greater than 61 decibels (dB), which is considered a significant level of hearing loss - Children of any gender - Children who score below 45 on a standard b...

Who might be able to join this trial: - You are 18 years old or younger. - For most study groups: you have a hearing threshold of 20 dB HL or higher based on behavioral or pure-tone hearing tests, or a hearing test called air-conduction ABR shows a threshold of 35 dB nHL or higher (confirm with trial site). - For the n...

Who might be able to join this trial: - The child must be between 9 months and 7 years old at the time of receiving the gene therapy - The child must have at least two faulty copies of a specific gene called GJB2 (one inherited from each parent) that are known or likely to cause hearing problems - The child must have h...

Who might be able to join this trial: - Children born between January 1, 2010 and December 31, 2025 who have a newborn blood spot sample stored from the Danish national newborn screening program - Children who tested positive for a birth infection called congenital CMV (cytomegalovirus), confirmed by a test done shortl...

**Who might be able to join this trial:** - People who have noticed difficulty hearing in noisy environments, lasting at least 6 months before the screening appointment - People who show a measurable difficulty understanding speech when there is background noise, in at least one ear - People whose hearing test results...

Who might be able to join this trial: - People who are 60 years of age or older - People whose hearing test results show hearing thresholds of 25 dB HL or better across several key sound frequencies in both ears (confirm with trial site) - People who have previously reported having difficulty hearing during an earlier...

**Who might be able to join this trial:** - People who are 18 years of age or older - People with mild to moderate-to-severe hearing loss in both ears, confirmed through hearing tests at the start of the study (specifically, a hearing level between 20 and just under 80 decibels in both ears) - People who are willing a...

**Who might be able to join this trial:** - People aged 18 years or older - People who had normal hearing at some point in their life before losing it, and now have severe to profound hearing loss in the ear(s) that received the implant - People who have had a CT scan of their cochlear implant electrode after surgery,...

Who might be able to join this trial: - Adults aged 18 or older - People who developed significant hearing loss in one ear after they had already learned to speak and understand language - People whose other (non-implanted) ear has very good hearing, with hearing levels better than 30 dB (a measure used by audiologists...

Who might be able to join this trial: - People aged between 18 and 75 years old who are awake, able to communicate, and able to understand and fill out questionnaires and follow study procedures - People whose main and only complaint is tinnitus (ringing or noise in the ears), and whose hearing test results show normal...