Prostate Cancer Trial, Recruiting NCT05574647 Sponsor: Imperial College London Condition: Prostate Cancer
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Prostate Cancer Trial, Recruiting

NCT05574647
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

First stage (initial scan):

  • You are 18 years of age or older (there is no upper age limit)
  • You have a prostate (this includes men born male, or transgender women who have never used hormone therapy to reduce testosterone)
  • Your doctor has referred you for a prostate MRI because of an abnormal rectal examination and/or a PSA blood test result that is considered raised — specifically: PSA of 3.0 or above if you are aged 50–69; PSA of 5.0 or above if you are aged 70 or older; or PSA of 2.5 or above if you are aged 45–49 and have a higher risk due to family history or ethnic background; and this blood test was taken within the last 6 months

Second stage (biopsy):

  • Your MRI scan from the first stage showed a suspicious area that doctors believe needs a tissue sample (biopsy) to investigate further

Who may not be able to join:

First stage:

  • Your PSA blood test result is above 50
  • You have had a prostate MRI scan or prostate biopsy in the last two years
  • You have already been diagnosed with prostate cancer
  • You are unable to have an MRI scan or the contrast dye used during MRI (confirm with trial site)
  • You have had both hips replaced
  • You are unable to have a biopsy carried out using an ultrasound probe inserted into the back passage (confirm with trial site)

Second stage (in addition to the above):

  • You do not wish to have a biopsy

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 0203 311 1673

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
2 November 2022
Est. completion
31 October 2025

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Randomisation 1: Proportion of clinically significant cancers detected in the randomised population of patients at risk.; Randomisation 2: Proportion of clinically significant cancers detected in the randomised population of patients biopsied for a suspicious MRI.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov