Phase 3 Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 or older
- People who received a clot-dissolving drug called tenecteplase through a drip for a stroke, and whose symptoms either stayed about the same, got worse, or fluctuated up and down significantly within 4 to 24 hours after that treatment
- People whose stroke symptoms are at a certain level of severity (a score of 4 or more on a standard stroke assessment scale) before being assigned to a treatment group in the trial
- People, or their family members, who are willing and able to sign a written consent form agreeing to take part
Who may not be able to join:
- People in whom bleeding inside the brain was found on a brain scan (CT or MRI) after receiving the clot-dissolving treatment
- People whose brain scans (CTA, MRA, or DSA) show a blockage in certain major blood vessels supplying the brain (confirm with trial site for the specific vessels involved)
- People whose stroke is confirmed or suspected to have been caused by a blood clot travelling from the heart or another source — this includes people with conditions such as atrial fibrillation, certain heart valve problems, a blood clot inside the heart, a weakened heart muscle, a hole between the upper chambers of the heart combined with a bulging wall between them, or a stroke of unknown cause with a high risk score for future clots
- People with a low platelet count (a type of blood cell that helps with clotting) below a certain level
- People with poor kidney function, where the kidneys are filtering blood at a rate below a certain threshold
- People who are pregnant or breastfeeding
- People with a known allergy to the drug tirofiban, or to nickel, titanium, or their alloys
- People with a pre-existing brain or psychiatric condition that makes it impossible to assess how their nervous system is functioning
- People with a pre-existing bleeding disorder, or severe disease of the heart, liver, or kidneys, or a serious blood infection (sepsis)
- People who have a brain tumour that is pressing on surrounding brain tissue (small tumours on the brain's outer lining may be considered separately — confirm with trial site)
- People with a brain aneurysm or an abnormal tangle of blood vessels in the brain (arteriovenous malformation)
- People with a serious illness where life expectancy is estimated to be less than 6 months
- People who are already taking part in another clinical trial
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Zhongming Qiu, MD, Sun Yet-sen University
Phone: +8618376635080
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Excellent functional outcome
Can't join this trial?
Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.