Phase 2 Ovarian Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are a woman aged 18 or older with ovarian, fallopian tube, or primary peritoneal cancer that has come back after previous treatment
• Your cancer has been confirmed by a pathologist as one of these specific types: high grade or low grade papillary serous, high grade or low grade mucinous, clear cell, or high grade endometrioid carcinoma
• You have previously received at least one chemotherapy treatment that included a platinum-based drug, and your cancer stopped responding to platinum-based treatment
• You have not previously received liposomal doxorubicin (a specific chemotherapy drug), and your doctor considers it a suitable treatment option for you
• Your cancer coming back has been confirmed through a biopsy, scan, or a blood test measuring a marker called CA-125
• You are expected to live for more than 6 months
• Your general health and ability to carry out daily activities is at a moderate level or better (confirm with trial site)
• Your heart is functioning at a healthy enough level, as shown by a heart scan (at least 55% ejection fraction)
• Your blood counts, liver, and kidney function are within acceptable ranges based on recent blood tests
• You are not pregnant, not breastfeeding, and are either unable to become pregnant or are willing to use reliable contraception during the study and for 6 months after treatment ends
• You are willing and able to attend all required study visits and live close enough to the trial site to do so
• You have stopped any previous cancer treatments at least 4 weeks before joining the study and have recovered from their side effects
• You may have had surgery to remove tumours, radiation therapy, or previous anthracycline-type chemotherapy drugs and may still be eligible (confirm with trial site)

Who may not be able to join:

• You are in very poor health and have significant limitations in daily activities (confirm with trial site)
• You are pregnant or breastfeeding
• You have received another experimental treatment within the past 4–6 weeks (depending on the type)
• You have cancer that has spread to the brain or the lining of the brain, whether treated or untreated
• You have a known fluid build-up around your heart (pericardial effusion)
• You have an active serious infection or another serious illness, such as heart failure, that could make participation unsafe
• You have had another type of cancer in the past, unless it was a very early-stage cervical condition or a non-melanoma skin cancer, or unless the other cancer was fully treated at least 2 years ago with no signs of return
• You have a condition that causes active or ongoing bleeding
• You are currently receiving other cancer treatments
• You are already taking part in another clinical trial of an experimental treatment
• You have a serious infection, blood poisoning, or active hepatitis
• You have been diagnosed with congestive heart failure, unstable angina, or have had a heart attack in the past 6 months
• You have a known significant disease affecting the lining around your heart
• You are taking medications known to affect your heart's electrical system
• You have a known allergy to the study drug (WFA/ASWD)
• You have previously been treated with liposomal doxorubicin
• You have previously received other anthracycline or anthracenedione type chemotherapy drugs (confirm with trial site, as prior use may affect eligibility depending on dosage)
• Your doctor believes for any other reason that joining the trial would not be safe or appropriate for you

Important: Always verify eligibility with the trial site directly before applying.