Pulmonary Hypertension Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
Group 1 – Babies with lung disease and/or high blood pressure in the lungs (BPD±PH):
- The baby was born at 30 weeks of pregnancy or earlier
- The baby has reached at least 32 weeks of corrected age (counting from the original due date)
- For babies who also have high blood pressure in the lungs, an ultrasound of the heart must show evidence of this condition
- The baby needs breathing support (through a tube or a mask/device) for more than 12 hours a day, for at least 2 days, at a level above a certain threshold (confirm with trial site)
- A parent or legal guardian has given written consent to participate
Group 2 – Babies recovering from a serious bowel condition requiring surgery (surgical NEC):
- The baby was born at 30 weeks of pregnancy or earlier
- The baby is recovering from a severe form of a bowel condition called NEC, which required surgery
- The baby is able to tolerate a small amount of milk or feeding through the gut each day
- The baby is considered medically stable by their care team
- A parent or legal guardian has given written consent to participate
Who may not be able to join:
Group 1:
- The baby has a significant heart defect present from birth (small holes in the heart or a small open vessel near the heart may be allowed — confirm with trial site)
- The baby has a narrowing of the veins that carry blood from the lungs to the heart
- The baby currently has a serious infection that is affecting their blood pressure and circulation
- The baby is not expected to survive the next 7 days
- The baby has any other condition that the doctor feels could put them at risk or affect their ability to take part in the study
Group 2:
- The baby has a significant heart defect present from birth (small holes in the heart may be allowed — confirm with trial site)
- The baby has a narrowing of the veins that carry blood from the lungs to the heart
- The baby currently has a serious infection that is affecting their blood pressure and circulation
- The baby is not expected to survive the next 7 days
- The baby has another condition (unrelated to being born early or the bowel condition) that is significantly affecting how their lungs work
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Estelle Gauda, MD, Division Head, Division of Neonatology
Phone: +1(416)-813-7654
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Safety of oral L-Citrulline administration
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.