Phase 3 Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are a man or woman aged 50 years or older
- A doctor has determined that you are likely to have one year or less to live due to a serious end-stage illness, such as advanced dementia, end-stage heart failure, end-stage lung disease (COPD), or end-stage cancer
- You (or a legally authorized person acting on your behalf) are willing and able to sign a consent form agreeing to take part in the study, including agreeing to donate your brain after death, in line with the laws of the state where you live
- You are physically able to tolerate the study procedures, including lying still inside a PET scanner — the study doctor will assess this carefully for each person
Who may not be able to join:
- You are currently receiving aggressive, life-sustaining treatments such as curative chemotherapy (note: palliative chemotherapy, meaning treatment to manage symptoms, is allowed)
- You are known to have a significant structural problem in the brain — such as a large stroke, brain tumor, cyst, or other lesion — that could interfere with brain scans or brain tissue assessment (cases like this may need to be discussed with the study team before a decision is made)
- You have brain problems thought to be caused by long-term heavy alcohol use or severe liver disease
- Your kidneys are functioning at a very low level (a specific kidney function measurement called GFR is below 15 mL/min)
- You have previously received any approved or experimental treatment specifically designed to target amyloid or tau proteins in the brain
- You are a woman who could become pregnant and are currently pregnant, breastfeeding, or not using adequate birth control
- You have certain metal implants or devices in your body — such as a pacemaker, insulin pump, cochlear implant, or certain other implants — that have not been certified as safe for MRI, or you have a history of severe claustrophobia in an MRI scanner (this applies if an MRI scan is planned as part of your participation)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Alireza Atri, MD, PhD, Banner Health
Phone: +49 (0)30 461 1246 03
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Diagnostic Efficacy of the visual assessment of [18F]PI-2620 PET imaging, in correctly differentiating tau neurofibrillary pathology associated with AD (NFT Score of B0 or B1 = negative)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.