Phase 1 Prostate Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are able to understand and are willing to sign a written consent form agreeing to participate
• People who have been diagnosed with prostate cancer confirmed by a tissue sample
• People whose cancer cells produce a protein called PSMA, confirmed by laboratory testing
• People who are reasonably active and able to carry out daily activities (based on a standard medical fitness scale rated 0–2)
• People whose blood oxygen level is above 90% when breathing normal air
• People whose liver is working well enough, based on blood test results within acceptable ranges
• People whose kidneys are working well enough, based on a blood test measuring creatinine levels below 2.0 mg/dl
• People whose heart is pumping well enough, with the heart's pumping strength (ejection fraction) at 50% or above
• People whose red blood cell levels (haemoglobin) are at or above 80g/L
• People who have recovered from side effects of their most recent treatment, with at least 7 days since their last chemotherapy and at least three half-lives passed since their last immunotherapy (confirm with trial site)

Who may not be able to join:

• People who have another type of cancer or a serious unrelated medical condition
• People who are currently participating in another clinical drug trial, or receiving gene therapy or cell therapy
• People who have an active infection that is not under control
• People who have an active hepatitis B or hepatitis C infection
• People who have HIV
• People who are currently taking immune-suppressing medications or steroid tablets or injections (not including inhaled steroids)
• People who have a serious heart condition or a history of severe stroke or other major brain blood vessel disease
• People who have a condition present from birth that affects the immune system, or a condition affecting bone marrow function
• People who have an active autoimmune disease (such as connective tissue disease, eye inflammation, inflammatory bowel disease, or multiple sclerosis), or a history of severe autoimmune disease that required long-term immune-suppressing treatment
• People who have another active health condition that, in the treating doctor's judgement, would significantly raise the risk of serious complications from this treatment

Important: Always verify eligibility with the trial site directly before applying.