Phase 1 Alzheimer's Disease Trial, Recruiting NCT05667649 Sponsor: Regeneration Biomedical, Inc. Condition: Alzheimer's Disease
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Phase 1 Alzheimer's Disease Trial, Recruiting

NCT05667649
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 45 and 80 years old
  • You have been diagnosed with mild to moderate Alzheimer's disease
  • You have an adequate level of cognitive (thinking and memory) ability as assessed by the trial team
  • Your routine blood and lab test results are within a normal range
  • You are able to understand and willingly sign a consent form agreeing to take part
  • Your memory problems are not caused by a tumor or other separate disease
  • Any other health conditions you have are well-managed, and your medications have been stable for at least 3 months
  • You are in generally good overall health
  • You have a family member or caregiver who can support you during the trial
  • You are able to have a small amount of fat tissue removed (a minor procedure) to be used in creating the treatment
  • Your caregiver also meets the trial's own separate requirements for caregivers (confirm with trial site)

Who may not be able to join:

  • You are taking medications for Alzheimer's disease other than certain allowed ones — donepezil, memantine, AChEIs (including patches), Vitamin E, fish oil, and/or ginkgo biloba are permitted if the dose has been unchanged for at least 3 months before screening
  • You have received any type of stem cell treatment in the past 3 months
  • You have a device called a ventriculoperitoneal shunt already in place in your brain
  • You have a neurological (brain or nervous system) condition other than Alzheimer's disease
  • You have a psychiatric condition such as schizophrenia, bipolar disorder, depression, or delirium
  • You have had a problem with drug or alcohol misuse or dependence within the past 5 years
  • You have had a cancer diagnosis within the past 5 years
  • You do not have a caregiver available who meets the trial's requirements for caregivers

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Regeneration Biomedical, Inc.
Registry
ClinicalTrials.gov
Start date
14 August 2023
Est. completion
1 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

The safety of RB-ADSC treatment in study participants with AD

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov