Glaucoma Trial, Recruiting NCT05685485 Sponsor: Washington University School of Medicine Condition: Glaucoma
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Glaucoma Trial, Recruiting

NCT05685485
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years old or older
  • Your glaucoma or high eye pressure is not well controlled with current treatment
  • Your doctor has planned for you to have an Ahmed valve implant (a small drainage device placed in the eye)
  • You have been diagnosed with a specific type of glaucoma, including primary open angle glaucoma, primary angle closure glaucoma, or glaucoma related to protein buildup, pigment, or an eye injury — with or without having had previous eye surgery that did not fully work
  • This would be your first time having this type of drainage device implanted
  • You are able and willing to give your consent to take part

Who may not be able to join:

  • You have no light perception at all in the affected eye (completely no vision)
  • You are unable or unwilling to give your informed consent
  • You are not able to attend regular follow-up appointments
  • You have previously had a procedure that used heat, cold, or laser to destroy part of the eye's fluid-producing tissue (confirm with trial site)
  • You have had a previous procedure involving a band placed around the outside of the eye, or anything else physically blocking where the drainage device would be placed
  • You have silicone oil currently present in your eye
  • You have gel-like fluid from the back of the eye that has moved to the front of the eye and would require surgical removal
  • Your glaucoma is caused by eye inflammation (uveitis)
  • Your glaucoma is caused by abnormal blood vessel growth in the eye
  • You have an unusually small eye (a condition called nanophthalmos)
  • You have a condition that raises the pressure in the blood vessels around your eye (confirm with trial site)
  • Your planned eye surgery involves anything other than glaucoma drainage device implantation, or cataract removal at the same time
  • You have any other eye condition (apart from glaucoma) that could affect the accuracy of eye pressure measurements

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: James Liu, MD, Washington University St. Louis MO

Phone: 314-286-2946

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
18 October 2022
Est. completion
18 December 2024

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

IOP Change

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov