Phase 2 Breast Cancer Trial, Recruiting NCT05692674 Sponsor: Shanghai Proton and Heavy Ion Center Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Recruiting

NCT05692674
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with breast cancer confirmed by a tissue or cell test (pathology)
  • People who have had a mastectomy (surgical removal of the breast) with implant-based reconstruction and whose doctors have recommended radiation therapy afterward
  • People whose cancer has not spread to distant parts of the body
  • People who have never had radiation therapy to the chest or breast area before
  • People between the ages of 18 and 80
  • People in reasonably good general health, with no serious lung, heart, or blood vessel conditions that could interfere with radiation treatment
  • Women who are not pregnant (as confirmed by a blood or urine test) and are not currently breastfeeding
  • People who are willing to sign a consent form agreeing to receive radiation therapy as part of the trial

Who may not be able to join:

  • People whose breast cancer has not been confirmed by a tissue or cell test (pathology)
  • People whose cancer has spread to distant parts of the body
  • People who have previously had radiation therapy to the chest or breast area
  • People where the surrounding healthy organs cannot be kept within a safe radiation dose limit (confirm with trial site)
  • Women who are pregnant (confirmed by a blood or urine test) or currently breastfeeding
  • People in poor general health, based on standard health scoring scales used by doctors
  • People with serious existing health conditions, including: unstable chest pain, heart failure, or a heart attack requiring hospitalisation in the past 6 months; an active bacterial or widespread fungal infection; a flare-up of chronic lung disease or other breathing problems requiring hospitalisation; a weakened immune system; or a connective tissue disease such as active scleroderma or lupus that may make radiation therapy unsafe
  • People who are unable to understand the purpose of the treatment, or who are unwilling or unable to sign a consent form

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

GP referral letter

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Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Shanghai Proton and Heavy Ion Center
Registry
ClinicalTrials.gov
Start date
10 January 2023
Est. completion
1 September 2028

Where this trial is recruiting

🇨🇳 China

Primary endpoints

the failure rate of breast reconstruction after hypofractionated proton radiotherapy

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov