Stroke Trial, Recruiting NCT05727930 Sponsor: Indiana University Condition: Stroke
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Stroke Trial, Recruiting

NCT05727930
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who had a stroke between 1 and 6 months ago
  • People who have weakness on one side of their body (but not due to problems with the cerebellum, a part of the brain that controls balance and coordination)
  • People who are able to walk at least 10 meters (with or without help from another person, a walking aid, or a brace below the knee), but whose walking speed is slower than 1 meter per second
  • People who can sit without using their arms for support or needing someone to help them, for at least 30 seconds
  • People who can follow a 3-step instruction
  • People who have been cleared to participate by a supervising doctor or medical provider, and who have given their consent to join
  • People who are able to give their own consent, or who have a legally appointed representative who can consent on their behalf

Who may not be able to join:

  • People with serious heart, metabolic, or breathing conditions that prevent them from exercising safely — for example, a heart attack within the last 3 months, uncontrolled heart failure, very high resting blood pressure (above 210/110 mmHg), uncontrolled diabetes, advanced kidney disease, severe infection, serious psychiatric illness, or advanced cancer
  • People who show certain warning signs during an initial treadmill exercise assessment that require the test to be stopped — such as moderate to severe chest pain or specific abnormal heart readings (confirm with trial site)
  • People who had a bone, joint, or neurological condition before their stroke that already limited their ability to walk more than 50 meters
  • People who are receiving physical therapy once the baseline testing period has begun
  • People who are prescribed botulinum toxin (a muscle-relaxing injection) in leg muscles above the knee at a dose higher than 50 units in any single muscle — note that people receiving higher doses in muscles below the knee may still be considered, but would be required to wear an ankle-foot brace during the trial (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: George Hornby, Indiana University

Phone: 317-329-2353

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
11 January 2023
Est. completion
15 October 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Changes in 6 minute walk test

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov