COPD Trial, Recruiting NCT05743582 Sponsor: University of Edinburgh Condition: COPD
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COPD Trial, Recruiting

NCT05743582
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For people with COPD:

  • People with COPD between the ages of 18 and 77, with a mild to moderate-severe disease stage (GOLD Stage 1, 2, or 3), who are already having a bronchoscopy (a camera procedure into the airways) for a medical reason
  • People with COPD between the ages of 18 and 77, with a mild to moderate-severe disease stage (GOLD Stage 1, 2, or 3), who would only be donating blood for the study
  • People with COPD between the ages of 18 and 69, with a mild to moderate disease stage (GOLD Stage 1 or 2), who would be having a bronchoscopy purely for research purposes
  • COPD must have been confirmed by a chest X-ray or a detailed CT scan of the chest within the past 12 months
  • People who are able to give informed consent to participate

For healthy volunteers:

  • Any healthy person between the ages of 18 and 77
  • People who are able to give informed consent to participate

Who may not be able to join:

For people with COPD:

  • People who have an active cancer, a weakened immune system, diabetes, chronic kidney disease, or liver failure
  • People with a history of anaemia (low red blood cell levels)
  • People who have donated more than 250 ml of blood for any reason in the past 6 months
  • People who are pregnant or breastfeeding
  • People currently taking part in another clinical trial, unless that trial is directly related to this study
  • People who have had a fever or signs of an active infection (such as a respiratory, gut, or skin infection) in the past 2 weeks
  • People who have received a vaccine in the past 2 weeks
  • People who are unable to communicate in English or cannot clearly express willingness to take part
  • For those having a bronchoscopy: people with an active lung infection, lung cancer, significant scarring of the lung tissue, or any additional lung condition beyond COPD that would make the procedure unsafe (confirm with trial site)

For healthy volunteers:

  • People who have an active cancer, a weakened immune system, diabetes, chronic kidney disease, or liver failure
  • People found to have anaemia on a blood test taken at the screening visit
  • People who have donated more than 250 ml of blood for any reason in the past 6 months
  • People who are pregnant or breastfeeding
  • People currently taking part in any other clinical trial
  • People who have had a fever or signs of an active infection (such as a respiratory, gut, or skin infection) in the past 2 weeks
  • People who have received a vaccine in the past 2 weeks
  • People with any chronic or acute (sudden) breathing or lung condition
  • People with any ongoing medical condition or who regularly take prescription medication, except for the oral contraceptive pill
  • People who are unable to communicate in English or cannot clearly express willingness to take part
  • For those having a bronchoscopy: people with any active lung condition including lung infection or asthma, any significant abnormality on a chest X-ray that would make the procedure unsafe, or a lung function reading below 65% of what would be expected for their age and size (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: David H Dockrell, MD, University of Edinburgh

Phone: +441312426213

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Edinburgh
Registry
ClinicalTrials.gov
Start date
11 May 2023
Est. completion
1 December 2027

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Identification of immunometabolic responses in immune cells required for microbicidal activity.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov