Pulmonary Hypertension Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are able to give written consent before any study procedures begin.
- People who are able to lie comfortably on their back for up to 90 minutes at a time.
- Women who could become pregnant may be eligible if a sensitive pregnancy test comes back negative and a highly effective form of contraception (other than the oral contraceptive pill) is being used for the required period.
- Men who could father a child may be eligible if they are willing to follow the contraception requirements set out by the trial.
Who may not be able to join:
- People who are unable to give informed consent, or who are not fluent English speakers.
- People with a specific genetic variation called the "TT genotype" at the rs6971 location on their DNA (confirm with trial site).
- People with significant kidney disease, indicated by a certain blood test result falling below a specified level.
- People with significant liver disease, indicated by liver enzyme levels more than twice the normal upper limit.
- People with anaemia, confirmed by a low haemoglobin level on a blood test.
- People who have sickle cell disease or thalassaemia (inherited blood conditions).
- People with a history of uncontrolled high blood pressure.
- People with an active infection of any kind, including eye, dental, or skin infections.
- People with chronic inflammatory conditions, including HIV or Hepatitis B.
- Women who are currently pregnant or breastfeeding.
- People who have taken part in another clinical drug trial within 5 half-lives of the last dose of that drug, or within one month — whichever is the longer period.
- People who have taken part in a research study involving significant radiation exposure within the last 3 years.
- People who have had significant radiation exposure (other than dental X-rays) within the last year.
- People with a positive Allen's test result (a test relating to blood flow in the hand — confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
The specific and non-specific fractions of the [11C]PBR28 signal in the lungs of healthy individuals and PAH patients.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.