Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
For people with Mild Cognitive Impairment (MCI):
- People aged 60 or older
- People who speak English fluently
- People who are able to give their own consent to take part in the study
- People who are willing and able to come back for a follow-up visit 2 years later
- People who are willing and able to bring a family member, friend, or carer who can take part in the screening and 2-year visits
- People with a body mass index (BMI) between 17 and 30 (a measure of body weight relative to height)
- People who meet the recognised medical definition of Mild Cognitive Impairment (MCI), based on criteria from the National Institute on Aging and the Alzheimer's Association, including: a noticeable change in thinking or memory reported by the person, a family member, or a doctor; measurable difficulties in one or more areas of thinking, often including memory; the ability to still manage everyday tasks independently; and signs suggesting the MCI may be related to Alzheimer's disease
For Study Partners (the family member, friend, or carer who accompanies the person with MCI):
- People aged 21 or older
- People who are able to take part in an interview
- People who are willing and able to attend study visits
- People who are willing and able to return for the 2-year follow-up visit
Who may not be able to join:
For people with Mild Cognitive Impairment (MCI):
- People who currently smoke
- People who have a current or past diagnosis of a major psychiatric condition, such as schizophrenia, bipolar disorder, obsessive-compulsive disorder (OCD), or post-traumatic stress disorder (PTSD)
- People who have a neurological condition such as Parkinson's disease or Huntington's disease
- People who have a current or past immune system disorder, such as multiple sclerosis
- People who have a current or past history of drug dependence
- People who have been treated with certain medications — including antipsychotics, sleep medications, or steroid-based anti-inflammatory drugs — within the last six months (confirm with trial site)
- People who have had a head injury that caused them to be unconscious for more than 30 minutes, or who have a history of stroke or seizures
- People who have had general surgery within the last 3 months
- People with significant vision or hearing difficulties that would interfere with completing cognitive tests
For Study Partners:
- People who are not willing to answer questions about the person with MCI they are accompanying
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Cynthia A Munro, PhD, Johns Hopkins School of Medicine
Phone: 410-550-6271
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in mean memory test composite score; Change in mean executive test composite score
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.