Oesophageal Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are willing to agree to the trial conditions in writing and are able to follow the treatment plan and attend follow-up appointments
• People aged between 18 and 75 years old (any gender)
• People who have been diagnosed with esophageal squamous cell carcinoma (a specific type of oesophageal cancer) confirmed by laboratory testing of cells or tissue
• People with stage II or stage III oesophageal cancer who have not had surgery (other than a biopsy) to treat it
• People whose main tumour can be measured and assessed
• People whose cancer has not spread to distant organs in the body
• People with a moderate to severe nutritional risk or malnutrition, based on a specific nutritional assessment score (PG-SGA score B or C)
• People with a reasonably good level of physical functioning, based on standard medical scoring tools (confirm with trial site)
• People whose blood counts fall within acceptable ranges, without having needed a blood transfusion in the past 14 days — including haemoglobin, white blood cells, neutrophils, and platelets all meeting minimum levels (confirm with trial site for exact values)
• People whose liver and kidney function blood tests fall within acceptable ranges, including bilirubin, liver enzymes, and creatinine levels (confirm with trial site for exact values)
• People who are expected to live for at least 6 months

Who may not be able to join:

• People who show no signs of malnutrition or nutritional risk (those with a PG-SGA nutritional score of A)
• People with severely reduced bowel function, or who cannot tolerate feeding through the digestive system
• People experiencing severe vomiting, gastrointestinal bleeding, or a blocked bowel
• People whose malnutrition is so severe that they would not be able to tolerate radiation or chemotherapy
• People whose oesophageal tumour or nearby lymph nodes have previously been treated with radiotherapy, chemotherapy, or targeted therapy
• People who have had another cancer within the past 5 years (with exceptions for certain fully treated early-stage cancers — confirm with trial site)
• People who have participated in another drug trial within the past month
• People with a history of severe allergic reactions or unusual sensitivities to substances
• People with a history of severe lung or heart disease
• People with serious ongoing health conditions such as uncontrolled high blood pressure or heart failure
• People who are pregnant or breastfeeding
• People who are currently participating in, or planning to join, another clinical trial
• People who are unwilling or unable to sign the informed consent form

Important: Always verify eligibility with the trial site directly before applying.