Alzheimer's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been newly diagnosed with mild or moderate dementia, based on specific memory and thinking tests carried out by a licensed specialist
• People who have been clinically diagnosed by an expert neurologist as having probable Alzheimer's disease, using established medical guidelines
• People who have never taken certain Alzheimer's medications (acetylcholinesterase inhibitors or memantine), or who have not taken these medications in the past three months — except if they stopped due to a bad reaction to the medication
• People who are 65 years old (confirm with trial site whether this means exactly 65 or 65 and older)
• People who live in the National Capital Region
• People who are able to read and understand written and spoken English and Filipino

Who may not be able to join:

• People whose dementia is caused by structural or blood vessel-related brain changes, other than a small number (two or fewer) of minor lesions seen on a brain scan
• People whose dementia has been diagnosed as something other than Alzheimer's disease by an expert neurologist
• People who have had untreated depression or related mental health conditions in the past 6 months
• People who have taken antibiotic medications in the three months before providing a stool sample for the trial
• People who have used steroids, immune-boosting medications, or immune-suppressing medications in the past 2 weeks, or who regularly need these medications for immune-related conditions
• People who have used certain stomach or bowel medications — including proton-pump inhibitors, H2-receptor antagonists, certain antidepressants, narcotic pain medications, anticholinergic drugs, laxatives, or anti-diarrhoeal medications — in the past 4 weeks
• People who consume large amounts of commercial probiotic products (108 colony-forming units or organisms per day or more)
• People who have made a major change to their diet in the past month, such as completely removing or significantly increasing a major food group
• People who have had major surgery on their digestive tract in the past 5 years (removal of the gallbladder or appendix are exceptions)
• People who have had a major portion of their bowel surgically removed at any point in their life
• People who have active, uncontrolled digestive or bowel conditions, such as inflammatory bowel disease, irritable bowel syndrome, ongoing infections of the gut, recurring bowel infections, or chronic constipation

Important: Always verify eligibility with the trial site directly before applying.