Osteoarthritis Trial, Recruiting NCT05840887 Sponsor: Istituto Ortopedico Rizzoli Condition: Osteoarthritis
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Osteoarthritis Trial, Recruiting

NCT05840887
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People between 20 and 60 years of age, male or female
  • People diagnosed with osteoarthritis affecting one compartment of the knee joint, at a moderate or lower level of severity (Kellgren-Lawrence grade 3 or below)
  • People whose knee alignment is off by more than 5 degrees, to a degree that a surgical bone-realignment procedure has been recommended
  • People who have a damaged or missing meniscus (the cartilage cushion in the knee) in the part of the knee affected by the misalignment
  • People who are able and willing to take part in a rehabilitation program and attend follow-up appointments, including X-rays and MRI scans
  • People who have signed a formal consent form agreeing to take part in the trial

Who may not be able to join:

  • People who have a condition that limits their ability to participate, or a neurological (brain or nerve) disorder that could affect the research results
  • People who have been diagnosed with any form of cancer
  • People diagnosed with certain joint or inflammatory conditions, such as rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, Reiter's syndrome, or arthritis caused by another inflammatory disease; or people with HIV, viral hepatitis, or a condition called chondrocalcinosis (calcium deposits in the joints)
  • People with diabetes that is not well controlled
  • People with a thyroid condition that is not well controlled
  • People who have problems with alcohol, drug, or medication misuse
  • People with a Body Mass Index (a measure of body weight relative to height) above 40
  • People who are pregnant, breastfeeding, or planning to become pregnant during the study period
  • People who have had knee surgery within the past 12 months

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 6366567

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Istituto Ortopedico Rizzoli
Registry
ClinicalTrials.gov
Start date
30 August 2023
Est. completion
1 June 2026

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

IKDC-Subjective Score (Subjective International Knee Documentation Committee)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov