Pulmonary Hypertension Trial, Recruiting NCT05843500 Sponsor: University of California, San Francisco Condition: Pulmonary Hypertension
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Pulmonary Hypertension Trial, Recruiting

NCT05843500
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been referred with a condition called CTED or CTEPH — these are lung conditions caused by old blood clots that have not fully cleared, which can make the heart and lungs work harder and cause breathing difficulties.
  • People whose diagnosis is supported by at least one of the following: specific measurements of blood pressure in the lungs (taken during a heart procedure called a right heart catheterization) that are above certain levels, OR imaging scans (such as a VQ scan, CT scan, MRI, or pulmonary angiogram) showing signs of old blood clot disease in the lungs.
  • People who have difficulty exercising due to this chronic blood clot disease in the lungs, even if their resting lung blood pressure measurements are not elevated.
  • People who have been taking blood-thinning medication (anticoagulation) for at least 3 months before their diagnosis was confirmed.
  • People aged 18 years or older.

Who may not be able to join:

  • People whose high lung blood pressure is caused by something other than chronic blood clots (the trial is specifically for a type known as WHO Group 4 pulmonary hypertension).
  • People who do not wish to take part in clinical research or are not willing to receive the treatment being studied.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Miles Conrad, MD, University of California, San Francisco

Phone: (415) 353-1300

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 August 2023
Est. completion
1 July 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Total number of patients who survive; Changes in exercise tolerance; Changes in supplemental oxygen use severity; Changes in New York Heart Association (NYHA) functional class; European Quality of Life Five Dimension (EQ-5D) - Scale Score; Changes in patients' emPHasis-10 scores; Number of patients undergoing lung transplantation

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov