Osteoarthritis Trial, Recruiting NCT05848622 Sponsor: University of North Carolina, Chapel Hill Condition: Osteoarthritis
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Osteoarthritis Trial, Recruiting

NCT05848622
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have already finished all of your regular physical therapy sessions
  • You are between 16 and 35 years old
  • You had surgery to reconstruct your ACL (a ligament in the knee) between 6 and 60 months (up to 5 years) before joining the study
  • When you walk, your leg puts less force through the ground than expected — this would be measured and confirmed by the research team (confirm with trial site)

Who may not be able to join:

  • You had surgery on more than one knee ligament at the same time, such as the PCL (a ligament at the back of the knee)
  • You have had a fracture (broken bone) in your leg, such as a certain type of break at the top of the shin bone
  • You have been diagnosed with osteoarthritis (wear and tear of the cartilage) in your knee

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Brian Pietrosimone, PhD, University of North Carolina, Chapel Hill

Phone: 9199622025

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
13 June 2023
Est. completion
1 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Mean Change from Baseline to Week 6 in Vertical Ground Reaction Force; Mean Change from Baseline to Month 6 in Vertical Ground Reaction Force; Mean Change from Baseline to Week 6 in Knee Joint Contact Forces; Mean Change from Baseline to Month 6 in Knee Joint Contact Forces; Mean Change from Baseline to Week 6 in Tibial Cartilage Strain; Mean Change from Baseline to Month 6 in Tibial Cartilage Strain; Mean Change from Baseline to Week 6 in the Knee Injury and Osteoarthritis Outcome Quality of Life Subscale Score; Mean Change from Baseline to Month 6 in the Knee Injury and Osteoarthritis Outcom...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov