Vasculitis Trial, Recruiting NCT05854927 Sponsor: Fondation Ophtalmologique Adolphe de Rothschild Condition: Vasculitis
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Vasculitis Trial, Recruiting

NCT05854927
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You have been referred for an MRI scan with contrast dye (an injected MRI) because giant cell arteritis (GCA) is suspected
  • Your doctors suspect you may have GCA based on a combination of signs — either three "major" signs or two "major" plus one "minor" sign from the lists below:
    • Major signs: being over 50 years old; a new type of headache; pain or cramping in the jaw, tongue, or difficulty swallowing; vision problems such as sudden vision loss, double vision, or blurred vision; or blood test results showing high levels of inflammation markers
    • Minor signs: tenderness, thickening, or lumps on the scalp away from the temples; abnormal feel of the temporal artery (the artery near your temple) when touched; facial pain or a feeling of swelling in the face; general symptoms such as fever above 38°C, losing more than 10% of your body weight, loss of appetite, tiredness, or generally feeling unwell
  • You are willing and able to give your consent to take part in the study
  • You are covered by a social security or health insurance plan (French system)

Who may not be able to join:

  • You have been diagnosed with a cancer or malignant disease within the last year
  • You currently have an active infection
  • You have been diagnosed with certain autoimmune or inflammatory conditions, such as rheumatoid arthritis, lupus, or certain types of blood vessel inflammation (confirm with trial site for the full list)
  • You have been taking high-dose steroid medication (such as prednisone at a high dose) for more than 10 days
  • You have a reason why you cannot safely have an MRI scan (for example, certain metal implants or severe claustrophobia)
  • You are under a legal protection measure or guardianship arrangement
  • You are currently pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Fondation Ophtalmologique Adolphe de Rothschild
Registry
ClinicalTrials.gov
Start date
10 January 2024
Est. completion
1 June 2027

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Sensitivity of unilateral or bilateral inflammation of the temporal arteries and/or ophthalmic arteries or other branch of the internal carotid arteries with a 3D PDw MRI sequence for GCA diagnosis

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov