Phase 3 Oesophageal Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with a specific type of esophageal cancer (adenocarcinoma or squamous cell carcinoma) located in the middle or lower part of the esophagus, or at the point where the esophagus meets the stomach, and who are scheduled for surgery to remove the esophagus or to rebuild it using part of the stomach or small intestine.
- People aged 18 or older.
- People who are able to read and sign a consent form agreeing to participate in the study.
Who may not be able to join:
- People who are scheduled for emergency or "rescue" surgery rather than planned surgery.
- People whose planned surgery involves using part of the large bowel (colon) to rebuild the esophagus.
- People who are known or suspected to be pregnant.
- People who have had surgery on their upper digestive system within the 30 days before being enrolled in the trial.
- People who are unable to understand the study information or instructions, or who cannot give informed consent.
- People who are already enrolled in another clinical trial that could interfere with this one.
- People who have a known allergy, sensitivity, or harmful interaction with the study medication being tested.
- People who have a documented presence of certain antibiotic-resistant bacteria (specifically Enterobacteriaceae or Pseudomonas Aeruginosa that do not respond to tobramycin/gentamicin or carbapenem antibiotics).
- People who are undergoing a specific type of continuous kidney filtering treatment called CVVH (confirm with trial site).
- People with documented severe chronic kidney failure, or who are on regular kidney dialysis (either haemodialysis or peritoneal dialysis).
- Women who could become pregnant and are not using adequate contraception.
- People who are unable to swallow the study medication, which is taken by mouth.
- People who have a pre-existing degenerative neuromuscular condition, such as myasthenia gravis or Parkinson's disease.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Camiel Rosman, Prof, RadoudUMC
Phone: +31655740313
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
the cumulative incidence of postoperative pneumonia within 30 days after surgery
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.