Pulmonary Hypertension Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with COPD, confirmed by a specific breathing test showing airflow limitation (FEV1/FVC ratio below 0.7)
- People who are 40 years of age or older
Who may not be able to join:
- People who had a COPD flare-up or worsening of symptoms in the 3 months before joining the trial
- People whose COPD medications were changed in the 3 weeks before joining the trial
- People who need more than 6 litres per minute of supplemental oxygen while resting
- People who need more than 10 litres per minute of supplemental oxygen during physical activity
- People with active or uncontrolled heart or cardiovascular conditions, such as high blood pressure above 150/100 even with medication, chest pain from heart disease, weak heart pumping function, irregular heart rhythms, or significant heart valve problems
- People with signs of excess fluid in the body, such as swelling in the neck veins or noticeable swelling in the limbs
- People who are in the most severe functional class (Class IV) as classified by the World Health Organization, meaning they have symptoms even at rest
- People known to have high blood pressure in the lungs, with a mean pulmonary artery pressure above 45 mmHg
- People with untreated severe sleep apnoea or a condition where obesity affects breathing during sleep
- People with an active cancer (other than skin cancer)
- People with physical conditions that prevent them from exercising on an upright stationary bike, such as severe joint problems or balance issues
- People who are pregnant
- People with a body mass index (a measure of body weight relative to height) below 18 or above 40
- People whose blood cell concentration (haematocrit) is below 25% or above 55%
- For the invasive part of the exercise test only: people who take long-term blood-thinning medication that cannot be safely paused for the study visit
- For the invasive part of the exercise test only: people whose breathing test result (FEV1) is below 20% of the expected value (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Lindsay Forbes, MD, University of Colorado, Denver
Phone: (303)724-4020
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Right ventricular contractility measured by transthoracic echocardiography
Can't join this trial?
Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.