Lymphoma Trial, Recruiting NCT05898477 Sponsor: University of Alabama at Birmingham Condition: Lymphoma
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Lymphoma Trial, Recruiting

NCT05898477
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have lymphoma and also show signs of a serious immune overreaction called HLH (haemophagocytic lymphohistiocytosis), meeting at least one of the following two sets of conditions:
  • People whose condition meets 5 out of 8 specific medical signs listed in the HLH-2004 diagnostic guidelines (confirm with trial site for the full list of signs)
  • People whose blood test results show a specific protein level (sCD25) above 3,900 U/mL and a ferritin level above 1,000 ng/mL, which together indicate a positive result on a scoring system called the OHI index

Who may not be able to join:

  • People with an aggressive form of lymphoma whose HLH symptoms developed more than one month after their lymphoma was first diagnosed
  • People whose medical records do not fully document their treatment history and how their condition responded to treatment

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Gaurav Goyal, MD, University of Alabama at Birmingham

Phone: 205-934-1816

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 May 2023
Est. completion
1 January 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To determine the factors predicting 180 days overall survival of patients with cancer that are HLH-2004/OHI+

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov