Breast Cancer Trial, Recruiting NCT05914961 Sponsor: University Hospital Tuebingen Condition: Breast Cancer
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Breast Cancer Trial, Recruiting

NCT05914961
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Women aged 18 or older
  • People with a confirmed diagnosis of invasive breast cancer, whether early-stage, advanced, or metastatic, at any point in their treatment journey
  • People whose breast cancer tests negative for estrogen receptors (ER), progesterone receptors (PR), and HER2 protein (a type known as "triple-negative breast cancer")
  • People with advanced or metastatic disease in the experimental group whose tumour tests positive for a protein called PD-L1 at specific levels (confirm with trial site)
  • People in the experimental group for whom a treatment plan combining immunotherapy (ICI) and chemotherapy is being considered
  • People who have provided written consent to participate in the ICK-breast registry

Who may not be able to join:

  • People whose breast cancer tests positive for estrogen receptors (ER) or progesterone receptors (PR)
  • People whose breast cancer tests positive for the HER2 protein at specific levels confirmed by laboratory testing
  • Early-stage breast cancer patients who have already received any systemic (whole-body) breast cancer treatment before joining the trial
  • People who have already received immunotherapy (ICI) treatment before joining the trial
  • People who are currently pregnant or breastfeeding
  • People whose overall health is not considered strong enough to tolerate chemotherapy

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Tobias Engler, Dr., Department of Women's Health Tübingen

Phone: 07071 29 82211

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University Hospital Tuebingen
Registry
ClinicalTrials.gov
Start date
1 June 2024
Est. completion
1 April 2027

Where this trial is recruiting

🇩🇪 Germany

Primary endpoints

Prognostic value of CRP kinetics under ICI therapy on pathologic complete response (PCR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov